Establishing the Ukrainian Parkinson’s Disease Cohort within GP2: Early Results from the UPGRADE-PD Initiative
Objective: To describe the early establishment and recruitment outcomes of the Ukrainian Parkinson’s disease cohort within the Global Parkinson’s Genetics Program (GP2). Background: Eastern European…Gait Activation Improves Hypomimia in Parkinson’s Disease
Objective: To evaluate the effect of gait function activation on hypomimia in patients with Parkinson's disease (PD). Background: Hypomimia, a reduction in facial expressivity, is…Integrated and Multidisciplinary Care for Older Adults with Parkinson’s Disease: A value-driven approach
Objective: To evaluate value driven outcomes of an integrated multidisciplinary Parkinson’s clinic for older adults in Singapore Background: Parkinson’s Disease (PD) is a complex neurodegenerative…Mechanisms of PLA2G6 Deficiency Impacting Mitochondria-associated membranes in Parkinson’s Disease
Objective: This study aims to explore the functions of PLA2G6 protein at the endoplasmic reticulum-mitochondria interface, unveiling the potential mechanisms of PLA2G6-related Parkinson’s disease (PD)…Subtle Behavioral Changes Observed by Knowledgeable Informants Up to Decades Before Parkinson’s Disease Diagnosis
Objective: To characterize subtle behavioral changes observed by Knowledgeable Informants (KIs) of people with Parkinson’s disease (PwPD) before diagnosis. Background: Earlier identification of PD remains…3D Markerless Video-Based Assessment of Lower Extremity Dystonia in X-linked Dystonia Parkinsonism and DYT-TOR1A
Objective: To evaluate whether markerless video analysis can extract quantitative motor features that reflect dystonia severity in X-linked dystonia parkinsonism (XDP). Background: XDP is an…Parkinson’s Disease and Parkinsonism Family Center Psychoeducational Program for Patients and Caregivers
Objective: To provide structured psychoeducational and informational support, including disease education, coping and self-management strategies, and guidance on healthcare and social services for Parkinson’s disease…Differentiation of Parkinsonian Syndromes Using Cognitive Strategies and Associations with Non-tremor Motor Progression
Objective: This study aims to investigate whether cognitive strategies on verbal fluency tasks differentiate Parkinson’s disease (PD) from Progressive Supranuclear Palsy (PSP) and healthy adults, and are associated with the progression of clinical motor symptoms in Parkinson’s…DTI-ALPS Insights into Glymphatic Dynamics and Neurovascular Changes in Parkinson’s Disease
Objective: To investigate glymphatic activity, structural small vessel disease (SVD) markers, and white matter microstructure in Parkinson’s disease (PD) patients, and to explore their associations…Caudate-Predominant Striatal Dopaminergic Deficits in bvFTD with Parkinsonism
Objective: To characterize the dopaminergic lesion pattern in behavioral variant frontotemporal dementia with parkinsonism (bvFTD-P) using dopamine transporter (DAT) positron emission tomography (PET), and to…
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