Local Field Potentials (LFP) Insights in the Treatment of X-linked Dystonia-Parkinsonism with Deep Brain Stimulation of the Subthalamic Nucleus
Objective: To demonstrate sustained improvement in parkinsonism and dystonia in patients with X-linked Dystonia-Parkinsonism (XDP) after deep brain stimulation (DBS) of the subthalamic nucleus (STN)…Locus Coeruleus-Thalamic Circuit Degeneration in Parkinson’s Disease
Objective: This study characterizes the microstructural evolution of the locus coeruleus (LC) and its thalamic projection tract in Parkinson’s disease (PD) using free‑water imaging across…Very late-onset PKAN presenting with parkinsonism and lingual tremor at age 52
Objective: To report a very late-onset case of pantothenate kinase-associated neurodegeneration (PKAN) initially diagnosed as Parkinson’s disease. Background: PKAN, the most common form of neurodegeneration…Prevalence and neuroimaging presentations of Parkinsonism patients with p.R544C NOTCH3 mutation in Taiwan
Objective: To investigate the prevalence and neuroimaging findings of NOTCH3 p.R544C mutation in patients with Parkinsonism in Taiwan. Background: Cerebral autosomal dominant arteriopathy with subcortical…Current Landscape and Unmet Needs of Neuropallitive-Supportive Care for Parkinson’s Disease in Korea: A Multicenter Survey of Patients, Caregiver, and Physicians
Objective: This study evaluated awareness and perceptions of palliative care among patients with parkinsonism, their caregivers, and physicians in Korea, and identified factors associated with…The epidemiological study of multiple system atrophy beginning in Hokkaido, Japan 2014-2026
Objective: To investigate epidemiological information of multiple system atrophy (MSA) patients in Hokkaido by using the data from the Hokkaido Rare-disease Consortium for MSA Extended…Causes of Death and Clinical Predictors of Mortality in Parkinson’s Disease and Parkinsonism: A 30-Year Population-Based Study
Objective: To investigate causes of death and the impact of clinical predictors on mortality among patients with Parkinson’s disease (PD) and parkinsonism in a population-based…The Global Parkinsons Genetics Program: Expanding the Diversity of Neurological Disorder Data – 2026 Update
Objective: To broaden the available data for Parkinson's Disease (PD) and related disorders by integrating genetic data from more than 140,000 participants worldwide through genotyping…Restoring Dopaminergic Function: iPSC-derived MSCs Show Therapeutic Promise in Parkinson’s Disease Rat Model
Objective: This study looked into the therapeutic potential of human induced pluripotent stem cell derived mesenchymal stromal cells (iMSCs) in a MPTP induced Parkinson’s disease rat model. Background: PD…Quality of Life in Atypical Parkinsonian Disorders: Preliminary Results from a Multicentre Cross-Sectional Study in Sri Lanka (GP2 Collaboration)
Objective: To evaluate the functional status and factors influencing quality of life (QoL) among patients with atypical parkinsonian disorders (APD) in Sri Lanka. Background: Atypical…
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