Metabolic Syndrome is not Associated with Parkinson’s Disease Severity, but Individual Metabolic Components May Be
Objective: To investigate whether individual metabolic components are associated with motor, cognitive, and functional outcomes in Parkinson’s disease (PD). Background: Metabolic syndrome has been proposed…Development of a Parkinson’s Disease Dyadic Multidisciplinary Illness Management Program: Protocol for PATH Parkinson
Objective: This study describes the development of partnership-based assistive team-based healing (PATH) Parkinson, a chatbot-based multidisciplinary mobile application (app) designed for patient–caregiver dyads with Parkinson’s…Artificial Intelligence-Based Voice Analysis for Early Detection of Parkinson’s Disease: A Systematic Review
Objective: To evaluate the diagnostic performance of artificial intelligence (AI)-based voice analysis in detecting Parkinson’s disease. Background: Speech impairment is an early feature of PD.…Handwriting in PRKN-PD: A Study of Movement Control
Objective: To explore differences in movement control between PRKN-PD and gene-negative YOPD patients using a structured handwriting task. Background: Idiopathic Parkinson’s disease (IPD) symptoms are…A Phase I Multicenter Trial of a Novel Gene Therapy BBM-P002 for Parkinsons Disease
Objective: To evaluate the 12-month safety, tolerability, and preliminary efficacy of BBM-P002, a novel dual-optimized gene therapy, in participants with moderate-to-advanced Parkinson's disease (PD). Background:…Nocturnal hypokinesia in Parkinson’s disease: impact on sleep and quality of life
Objective: To assess the prevalence of nocturnal hypokinesia among people with Parkinson's disease (PD) and its impact on the quality of life of these patients.…Microstructural and functional abnormalities of Amygdala subregions in Parkinson’s Disease with impulse control disorder
Objective: To investigate amygdala subregional alterations associated with impulse control disorders (ICD) in Parkinson’s disease (PD) and to clarify the mechanistic role of the superficial…Posterior Cortical Hypometabolism in GBA1 Variant Carriers with and without Parkinson’s Disease
Objective: To investigate brain glucose metabolic patterns and their relationship with clinical features in GBA1 mutation carriers with PD (GBA-PD), asymptomatic carriers (GBA-nonPD), and PD…Distinct Cognitive Profiles in Parkinson’s and Alzheimer’s Disease: Evidence from a Large Neurodegenerative Cohort
Objective: To compare cognitive profiles across patients with Parkinson’s disease and Alzheimer’s disease using standardized neuropsychological assessment. Background: Cognitive impairment is a major feature of…Mapping the Temporal Evolution of Non-Motor Symptoms in Parkinson’s Disease: Findings from 100 Outpatient Cases Using a Single-Page Temporal Template
Objective: To describe the temporal sequence of Non-motor symptoms (NMS)relative to first motor symptom onset using a single-page, outpatient-friendly temporal profile template. Background: NMS often…
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