Interplay of sex and GBA1 and LRRK2 genotype in Parkinson disease progression
Objective: To characterize disease heterogeneity and how sex impacts motor and cognitive progression class membership across genetic subgroups of GBA1, LRRK2, and idiopathic Parkinson disease (PD). Background: Autosomal…Efficacy of Repetitive Transcranial Magnetic Stimulation for Improving Motor Function in Parkinson’s disease; A Prospective, Multicenter, Crossover Study
Objective: We aimed to investigate the effect of repetitive transcranial magnetic stimulation (rTMS) on the improvement of motor function in patients with Parkinson’s disease (PD).…Long-term evolution of deep brain stimulation parameters in Parkinson´s Disease: A 6-year analysis.
Objective: Characterize longitudinal evolution of Deep Brain Stimulation (DBS) parameters in patients with Parkinson´s Disease (PD) over a 6-year period and evaluate stability of programming…Real-World Experience with Continuous Subcutaneous Foslevodopa/Foscarbidopa (FLC/FCD) in Advanced Parkinson’s Disease: A Single-Centre Cohort Study
Objective: To evaluate efficacy, safety, and discontinuation rates of FLC/FCD in a retrospective cohort of advanced PD patients. Background: Continuous subcutaneous FLC/FCD is a novel…Modulated functional connectivity in patients with Parkinson’s disease by transcutaneous auricular acupoint Vagus Nerve Stimulation (taVNS)
Objective: To explore the brain function mechanism of rs-fMRI in the treatment of PD by taVNS. Background: TaVNS has the potential to improve the clinical…Effects of Repetitive Deep TMS on Motor Function and Cerebral Perfusion in Parkinson’s Disease
Objective: This study aimed to investigate the effects of deep repetitive transcranial magnetic stimulation (dTMS) using an H-coil on cerebral perfusion and motor function in…Exercise and SUTT: A 9-week randomized, double-blinded, controlled intervention on Parkinsonian Gait.
Objective: To determine the effect of exercise combined with self-initiated unclassified therapeutic tremors (SUTT), over 9 weeks, compared to exercise-alone, on gait in people with…Dual-Task Gait Costs do not Increase Across Stages of Parkinson’s Disease
Objective: To investigate whether motor and cognitive dual-task (DT) gait costs differ between early and intermediate stages of Parkinson’s disease (PD). Background: In PD, reduced…Disentangling Disease- and Medication-Associated Gut Microbiome Signatures in Parkinson’s Disease
Objective: To determine how Parkinson’s disease (PD) medications influence gut microbiome composition and function, and to distinguish microbiome features associated with PD pathology from those…Regional α-Synuclein Seeding Activity in Parkinson’s disease and Multiple System Atrophy
Objective: This study aimed to profile regional α‑synuclein (α-syn) seeding activity in postmortem brains from Parkinson’s disease (PD) and multiple system atrophy (MSA) and to…
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