Experiences with Adaptive Deep Brain Stimulation for Parkinson’s Disease in Routine Clinical Care
Objective: To evaluate initial experiences and (symptom-specific) outcomes with adaptive deep brain stimulation (aDBS) for Parkinson’s disease (PD) in routine clinical care across multiple international…Evaluating the Conversion of Immediate-Release and/or Extended-Release Levodopa to IPX203 in Patients with Parkinson’s Disease
Objective: This quality improvement (QI) project was conducted to evaluate the impact of the conversion from immediate-release (IR) and/or extended-release (ER) levodopa (LD) to mucoadhesive polymer…Longitudinal evolution of impulsive-compulsive behaviors and their prognostic value in Parkinson’s disease
Objective: To characterize longitudinal trajectories of impulsive-compulsive behaviors (ICD) in PD and to determine their prognostic value for quality of life and dopaminergic medication requirements…Safety of Opicapone After 10 Years of Post-Marketing experience Worldwide
Objective: To review the safety data of opicapone (OPC) after 10 years of worldwide marketing experience. Background: OPC, a third-generation COMT inhibitor, is approved as…Quantitative Analysis of the DESH in Normal Pressure Hydrocephalus and Parkinson’s Disease
Objective: To investigate whether Parkinson’s disease (PD) exhibits imaging features similar to normal pressure hydrocephalus (NPH) by comparison with healthy controls and NPH patients, and…Uncovering Sleep Neural Signatures of Parkinson’s Disease and REM Sleep Behavior Disorder from Polysomnography through Interpretable Deep Learning
Objective: To uncover sleep physiological signatures that distinguish Parkinson's disease (PD) and REM sleep behavior disorder (RBD) by reverse-engineering what a deep learning classifier learns…Clinical Relevance of Oral Health Assessment in Parkinson’s Disease Monitoring
Objective: To evaluate the clinical relevance of oral health assessment in Parkinson’s disease (PD) by determining whether oral inflammatory, microbial, and periodontal alterations are associated…Synuclein and dopamine transporter biomarkers among phenoconverters to parkinsonian disorders
Objective: To describe and assess biological congruency, defined as expected biological profile based on abnormal CSF α-synuclein Seed Amplification Assays (CSFaSynSAA) and dopamine transporter SPECT…Device-Assisted Therapies in Parkinson Disease: Patient Preference Following Nurse-Led Education
Objective: The study aims to evaluate treatment preferences and factors influencing decisions following structured Parkinson Disease Nurse Specialist (PDNS)-led Device Assisted Therapy (DAT) education. Background:…Altered Degree Centrality and Its Association with Neurotransmitter Systems in Parkinson’s Disease Patients with Impulse Control Disorders: A Resting-State fMRI Study
Objective: To characterize alterations in local brain function measured by degree centrality (DC) and to explore potential neurotransmitter information in PD patients with ICD (PD-ICD),…
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