Immunological principles of levodopa therapy in Parkinson’s disease
Objective: Study of the relationship between serum IL-10 levels in patients with Parkinson's disease and levodopa therapy Background: In Parkinson's disease, dehydroepiandrosterone can lead to…Levodopa-Induced Dyskinesias in Patients with Parkinson’s Disease in the Uzbek Population
Objective: To investigate the clinical features and prevalence of levodopa-induced dyskinesias in patients with Parkinson’s disease in the Uzbek population. Background: Levodopa-induced dyskinesias (LID) are…Impact of Caffeine Consumption on Clinical Phenotype and Non-Motor Symptoms in Parkinson’s Disease
Objective: To determine the impact of daily caffeine consumption (presence, quantity) on the clinical phenotype of patients with Parkinson’s Disease (PD), focusing on age of…Latent Classes of Cognitive Decline in Parkinson’s Disease: Neuroimaging and Neurodegenerative Blood Biomarker Correlates
Objective: To identify longitudinal trajectories of cognitive decline in Parkinson’s disease (PD) and to characterize neuroimaging and neurodegenerative blood biomarker correlates. Background: Cognitive impairment affects…Reduced Slow Wave Sleep is Associated with Mobility Impairment in People with Parkinson’s Disease
Objective: Determine relationships between functional mobility and slow wave sleep (non-REM stage 3; N3) in Parkinson’s disease (PD). Background: Sleep disturbance is a common non-motor…The Syn-Sleep Study: Detection of Cutaneous Phosphorylated Alpha-Synuclein in REM Sleep Behavior Disorder
Objective: The goals of this study are to 1) determine rates of phosphorylated alpha-synuclein (P-SYN) deposition in iRBD, 2) quantify changes in P-SYN deposition over…Biofluid Markers in Parkinson’s Patients and Correlation with Cognitive Profile
Objective: The purpose of this study was to determine potential biofluid biomarkers for cognitive impairment in a cohort of Parkinson's disease (PD) patients. Here we…Preliminary Genetic Spectrum of Parkinson’s Disease in the Israeli PD GENEration Cohort
Objective: To characterize the preliminary genetic spectrum of the Israeli PD GENEration cohort. Background: The PD GENEration study (NCT04994015) provides genetic testing and counseling for…The Relationship Between Neurobehavioral Profile and Cognitive Phenotype in Patients with Idiopathic Parkinson’s Disease Without Dementia.
Objective: To identify the neurobehavioral profile and cognitive phenotype in patients with Idiopathic Parkinson’s Disease without Dementia (IPDWD). Background: Depression is one of the most…Impact of Variants in ADH1B and ALDH2 on Parkinson’s Disease in Japan
Objective: We analyzed the relationship among prevalence of Parkinson’s disease, the variants in ADH1B and ALDH2, alcohol consumption and smoking per population among Japanese prefectures.…
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