Neurocognitive Functioning (NF) in a Patient with Idiopathic Parkinson’s Disease without Dementia (IPDWD). Subjected to Deep Brain Stimulation (DBS) and Treatment by Clinical, Functional and Advanced Neuropsychology.
Objective: To identify the Neurocognitive Functioning (NF) in a patient with IPDWD and intervened by DBS, and to analyze the impact of functional neurorehabilitation (FNR)…Effects of ATH434, a Clinical-Phase Small Molecule with Moderate Affinity for Iron, in a Parkinson’s Disease Model in Macaques
Objective: (1) Determine whether oral ATH434 improves motor performance in a non-human primate hemiparkinasonian model when administered after symptom onset. (2) Relate observations to changes…Baseline Variables Associated with Apomorphine Sublingual Film Retention
Objective: The aim of this analysis was to identify the baseline variables that differ between patients who completed Study CTH-301 and those who discontinued during…Moderators of aerobic exercise effects on motor symptoms in patients with Parkinson’s disease: a systematic review and meta-analysis
Objective: To investigate the difference in the effects of aerobic exercise on motor function in patients with Parkinson's disease (PD) according to exercise intervention protocols.…Long term evaluation of gluten-free diet in Parkinson´s disease patients
Objective: The primary aim of the project was to evaluate the effect of long-term administered gluten-free diet (GFD) on motor symptoms of Parkinson's disease (PD).…Identifying the Most Sensitive Patient-reported Items from the MDS-UPDRS that Predict Initiation of PD Medications in Early Disease
Objective: Objective: To determine the most sensitive combination of MDS-UPDRS Parts IB and II items that accurately predicted the clinically relevant target of dopaminergic therapy…Role of RNA splicing in Parkinson’s disease
Objective: To identify key molecular perturbations affecting medium spiny neuron functions and their role in the clinical symptoms of Parkinson’s disease (PD). Background: The degeneration…Serum levels of VEGF-C and ENDGLIN in Parkinson’s disease and their clinical relevance
Objective: To evaluate the differences in serum concentrations of neurovascular unit (NVU)-related cytokines between patients with Parkinson's disease (PD) and control subjects (Ctr) and to…PARKIN gene replacement by AAV-mediated gene delivery as a therapeutic modality for PARKIN-deficient early-onset familial Parkinson’s disease
Objective: Evaluate PARKIN gene replacement by adeno-associated virus (AAV) vector as a therapeutic modality in relevant disease models of early-onset Parkinson’s Disease (EOPD). Background: Biallelic…Mapping the distribution of neurotransmitters to resting-state functional connectivity in patients with Parkinson’s disease
Objective: To examine the associations between functional connectivity (FC), as measured by resting-state functional magnetic resonance imaging (rs-fMRI), and the spatial distribution of dopamine and…
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