Vestibulo-ocular reflex and cognitive dysfunction in denovo Parkinson’s disease
Objective: To investigate the relationship between cognitive function and vestibulo-ocular reflex (VOR) gain in denovo Parkinson’s disease (PD). Background: Saccades are rapid eye movements necessary…Determining Cerebrospinal Fluid Alpha-Synuclein Seed Amplification Assay Status from Demographics and Clinical Data
Objective: To develop models that determine likeliness of positive detection of pathologic alpha-synuclein (asyn) in cerebrospinal fluid (CSF) as measured by seed amplification assay (SAA)…Pregnancy and delivery in women with Parkinson’s disease: A case series
Objective: To explore pregnancy, delivery, birth outcomes and disease course throughout pregnancy in women with Early Onset Parkinson’s disease (EOPD) who underwent pregnancy after onset…Proposed framework to evaluate the ability of digital measures to track early stage Parkinson’s disease progression
Objective: To introduce a technical framework for evaluating digital measures for their ability to track Parkinson’s disease (PD) progression and apply the framework to digital…A Study of Age-related Changes in Galanin Expression in the Neuropil and Associated Boutons in the Human Locus Coeruleus.
Objective: To determine the age-effects on galanin (Gal)-enriched synaptic boutons and neuropil of human locus coeruleus (LC) using autopsied human tissues. Background: The LC has…Can We Rid Uganda of the Societal Myth That Parkinson’s Disease Is Witchcraft?
Objective: Educate rural Ugandans that Parkinson’s Disease (PD) is a scientific disorder, not contagious or the result of anything mystical Background: People with PD (PWP)…Nigral Neuroinflammation and Dopaminergic Neurons in PD, MSA and PSP: A Comparative Clinicopathological Study
Objective: To investigate nigral neuroinflammatory markers and dopaminergic neuron counts in parkinsonian disorders, comparing their profiles across conditions. Background: In degenerative parkinsonian disorders, the primary…Utilization of Skin Punch Biopsy for the Diagnosis of Alpha-synucleinopathy in Clinical Practice
Objective: To understand the use of skin punch biopsies for diagnosis and management of α-synucleinopathy within a large medical system. Background: Skin punch biopsy has…Prediction of Time-to-Phenoconversion to Parkinsonism in Idiopathic REM Sleep Behavior Disorder (iRBD)
Objective: To develop a tool for the prediction of time-to-phenoconversion in individuals with iRBD during the prodromal stage of parkinsonism. Background: Parkinson’s disease(PD) and dementia…The Challenges of Very Late-Onset Parkinson’s Disease: Perspectives from Patients, Primary Caregivers and Attending Physicians.
Objective: The purpose of this study is to investigate the difficulties faced by very late-onset patients with Parkinson’s disease (PD), caregivers and attending physicians, and…
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