Determining Cerebrospinal Fluid Alpha-Synuclein Seed Amplification Assay Status from Demographics and Clinical Data
Objective: To develop models that determine likeliness of positive detection of pathologic alpha-synuclein (asyn) in cerebrospinal fluid (CSF) as measured by seed amplification assay (SAA)…Pregnancy and delivery in women with Parkinson’s disease: A case series
Objective: To explore pregnancy, delivery, birth outcomes and disease course throughout pregnancy in women with Early Onset Parkinson’s disease (EOPD) who underwent pregnancy after onset…Proposed framework to evaluate the ability of digital measures to track early stage Parkinson’s disease progression
Objective: To introduce a technical framework for evaluating digital measures for their ability to track Parkinson’s disease (PD) progression and apply the framework to digital…A Study of Age-related Changes in Galanin Expression in the Neuropil and Associated Boutons in the Human Locus Coeruleus.
Objective: To determine the age-effects on galanin (Gal)-enriched synaptic boutons and neuropil of human locus coeruleus (LC) using autopsied human tissues. Background: The LC has…Can We Rid Uganda of the Societal Myth That Parkinson’s Disease Is Witchcraft?
Objective: Educate rural Ugandans that Parkinson’s Disease (PD) is a scientific disorder, not contagious or the result of anything mystical Background: People with PD (PWP)…Combined application of alpha-synuclein and 4-repeat tau seed amplification assays for the differential diagnosis of parkinsonian disorders
Objective: To assess alpha-synuclein (a-syn) and 4-repeat tau (4RT) seed amplification assay (SAA) positivity rates in biosamples from people with Parkinson’s disease (PD) and Progressive…Preventing Treatment Disruptions: The Crucial Role of Outpatient Nurses and Multidisciplinary Collaboration in Managing Skin Complications during Foslevodopa/Foscarbidopa Therapy
Objective: The objective of this research was to explore the pivotal role of outpatient nurses in mitigating skin complications and facilitating uninterrupted treatment for Parkinson's…Baseline and Longitudinal NSD-ISS Staging of the PPMI Cohort
Objective: To apply biological definition and Neuronal α-Synuclein Disease Integrated Staging System (NSD-ISS) to the PPMI baseline and longitudinal dataset. Background: The NSD-ISS Working Group…The impact of stimulation setting on Battery Longevity in Deep Brain Stimulation
Objective: This study aims to assess the estimated battery longevity and its determinants in Percept model of Deep Brain Stimulation (DBS) devices in patients diagnosed…Association between Parkinsonism, Parkinson’s Disease and Cognitive Impairment and Incidence of Dementia in People with Parkinsonism and Parkinson’s Disease in Latin America: A 10/66 Dementia Research Group Study
Objective: The study aimed to determine the cross-sectional and prospective associations between parkinsonism and Parkinson's disease with cognitive impairment and dementia in a large multi-country…
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