Pre-operative predominance of Tremor versus PIGD scores in drug OFF state predicts motor and non-motor outcomes of STN-DBS for Parkinson’s disease
Objective: To test the predictive value of predominance of tremor versus PIGD scores on the motor and non-motor outcomes of bilateral STN DBS for Parkinson’s…Integrated safety analysis of BIA-28-6156 phase 1 clinical trials (a novel allosteric activator of beta-glucocerebrosidase)
Objective: To describe the safety profile and tolerability of BIA-28-6156 observed during phase 1 clinical trials. Background: BIA-28-6156 is a novel allosteric activator of beta-glucocerebrosidase…Unveiling the Link between Stress-Related Disorders and Dysautonomic Symptoms in Parkinson’s Disease: A Cross-Sectional Study
Objective: To explore the link between post-traumatic stress disorders and dysautonomic symptoms in Parkinson's disease. Background: Parkinson's disease is a complex condition that can lead…Comparison of the MIBG uptake in the major salivary glands between progressive supranuclear palsy/corticobasal syndrome and Parkinson’s disease
Objective: To compare the MIBG uptake in the major salivary gland between progressive supranuclear palsy/corticobasal syndrome (PSP/CBS) and Parkinson’s disease (PD). Background: 123I-metaiodobenzylguanidine (MIBG) myocardial…Choroidal changes in Parkinson’s disease: A longitudinal follow up study
Objective: The objective of the study was to evaluate the longitudinal changes in the choroid layer of the eye in patients with Parkinson’s disease (PD).…Effect of the COVID-19 pandemic on gait and other motor and non-motor symptoms in people with Parkinson’s disease
Objective: To determine if the COVID-19 pandemic significantly impacted disease progression in people with Parkinson's disease (PwPD) Background: Few cross sectional and short-term longitudinal studies…A strategic training framework for building research capacity in the Global Parkinson’s Genetics Program (GP2)
Objective: To promote and facilitate learning internationally with resources and expertise to serve the training needs of the Global Parkinson’s Genetics Program (GP2;www.gp2.org) and its…Impact of endpoint selection on sample size calculations for disease-modifying clinical trials in Parkinson’s disease patients with GBA1 mutations
Objective: To assess clinical trial sample size estimations under variable simulated scenarios for Parkinson’s disease (PD) patients with mutations in the β-glucocerebrosidade gene (GBA1). Background:…The effect of subthalamic deep brain stimulation on response inhibition and voluntary action control depend on connectivity of the volume of activated tissue with the prefrontal cortex
Objective: The effect of subthalamic deep brain stimulation on response inhibition and voluntary action control depend on connectivity of the volume of activated tissue with…No laughing white matter: reduced integrity of the lateral nucleus basalis of Meynert pathway in Parkinson’s disease-related cognitive impairment
Objective: Investigate differences in white matter integrity of the nucleus basalis of Meynert (NBM) tracts in Parkinson’s disease (PD) patients who develop mild cognitive impairment…
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