Neuromelanin related 7T MRI of the locus coeruleus differs between Parkinson’s disease and controls
Objective: To compare the signal intensity of the substantia nigra and locus coeruleus on Magnetization Transfer 7T MRI between PD patients and healthy controls (HC)…IP-RT-QuIC Identify Disease-Specific Alpha-Synuclein Seeds in serum from patients with syncleinopathy
Objective: To examine whether alpha-synuclein (aSyn) seed exists in the serum and its potential as a serum biomarker. Background: Parkinson’s disease (PD) and Multiple system…The effect of cathodal transcranial direct current stimulation in the treatment of Levodopa-Induced Dyskinesias in Parkinson’s Disease: a preliminary report.
Objective: Our study aims to demonstrate the possible effect of transcranial direct current stimulation (tDCS) in the treatment of Levodopa-induced dyskinesias (LIDs) in patients with…Does sex affect worsening of cognitive and IADL functions in PD with and without PD-MCI?
Objective: To define how sex affects worsening of cognition and instrumental activities of daily living (IADLs) in a heterogeneous cohort of people with Parkinson’s disease…Impact of deep brain stimulation of the subthalamic nuclei on non-motor symptoms in Parkinson’s disease: a monocentric prospective study with a 12-month follow-up
Objective: The aim of the study is to evaluate the evolution of non-motor symptoms in Parkinson's disease (PD) in patients treated with deep brain stimulation…Multicenter, randomized, placebo-controlled, double-blind, parallel-group proof-of-concept study of lixisenatide in patients with early Parkinson’s disease (PD): the LIXIPARK trial (NCT03439943)
Objective: To evaluate the “disease-modifying” effect of lixisenatide as adjunct to antiparkinsonian medications in patients with early PD. Background: Lixisenatide, a glucagon-like peptide 1 receptor…The feasibility and efficacy of speech therapy via video call in patients with Parkinson’s disease: a preliminary study
Objective: To evaluate the feasibility and efficacy of video call-based speech therapy for patients with Parkinson’s disease (PD) with speech problems. Background: PD patients commonly…The natural history of Parkinson’s disease in LRRK2 G2019S carriers
Objective: To document differences between the evolution of self-reported symptoms and prodromal markers in LRRK2 G2019S carriers and non-carriers with and without Parkinson’s Disease (PD).…Management of Sigmoid Volvulus in Parkinson’s patients presenting to Royal Berkshire Hospital, Reading ,UK.
Objective: To evaluate acute management of volvulus in Parkinson’s Background: Constipation affects upto 50% of patients with Parkinson's and sigmoid volvulus is an under recognized…Demographic, clinical and genetic factors affecting amantadine response among patients with Parkinson disease
Objective: To identify factors that correlate with efficacy and tolerability of amantadine to predict therapeutic outcomes Background: Amantadine is the only commercially available medication to…
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