MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Parkinson’s"

  • 2022 International Congress

    Lymphocyte count/neutrophil-to-lymphocyte ratio and mild cognitive impairment in Parkinson’s disease

    E. Contaldi, L. Magistrelli, S. Gallo, C. Comi (Novara, Italy)

    Objective: The present study aimed to elucidate whether i) lymphocyte count and neutrophil-to-lymphocyte ratio (NLR) can discriminate Parkinson's disease (PD) patients from healthy controls (HC);…
  • 2022 International Congress

    Developing zebrafish CRISPR/Cas9 knockout models of Parkinson’s Disease to identify novel therapeutic targets.

    J. García-Fernández, L. López-Blanch, M. Irimia, F. de Santis, J. Terriente (Badalona, Spain)

    Objective: Human patients present punctual mutations and/or small deletions in genes that have been associated with Parkinson’s disease, namely, park1, park2, park6, park7, and park8.…
  • 2022 International Congress

    No evidence for the impact of SNCA rs356219 on Parkinson’s disease progression

    A. Szwedo, T. Stoker, M. Camacho, D. Backström, L. Forsgren, R. Lawson, A. Yarnall, C. Williams-Gray, A. Macleod, C. Counsell, OB. Tysnes, G. Alves, J. Maple-Grødem (Stavanger, Norway)

    Objective: To replicate findings from previous studies reporting an association between the α-synuclein (SNCA) rs356219 genetic variant and progression to key outcomes in Parkinson’s disease…
  • 2022 International Congress

    Real-World Deep Brain Stimulation Outcomes Using DBS Systems with Directionality and Multiple Independent Current Control

    T. Zesiewicz, M. Barbe, S. Paschen, C. Luca, C. Zhao, F. Ponce, J. Durphy, J. Ostrem, N. Tomycz, T. Prell, M. Siddiqui, L. Chen, R. Jain (Tampa, USA)

    Objective: We report clinical outcomes associated with the use of Deep Brain Stimulation (DBS) systems capable of directionality and Multiple Independent Current Control (MICC). Background:…
  • 2022 International Congress

    Imaging progressive peripheral and central dysfunction in isolated REM sleep behaviour disorder after 3 years of follow-up

    T. Fedorova, K. Knudsen, K. Andersen, J. Horsager, C. Skjærbæk, M. Otto, K. Svendsen, P. Borghammer (Aarhus N, Denmark)

    Objective: To image progression of intestinal dysfunction, cardiac sympathetic denervation, and dopaminergic nigrostriatal damage in patients with isolated REM sleep behaviour disorder (iRBD). Background: A…
  • 2022 International Congress

    Measuring what matters in Parkinson’s disease – validating real-world digital mobility outcomes for widespread adoption

    A. Yarnall, C. Schlenstedt, P. Ginis, H. Hildesheim, A. Mirelman, J. Hausdorff, A. Nieuwboer, H. Gassner, L. Alcock, P. Brown, H. Hunter, I. Neatrour, L. Sutcliffe, J. Winkler, J. Klucken, J. Kudelka, M. Gordon, C. Becker, W. Maetzler, L. Rochester (Newcastle, United Kingdom)

    Objective: To validate and support widespread adoption of real-world digital mobility outcomes (DMOs) to monitor mobility performance, disease progression and predict falls in patients with…
  • 2022 International Congress

    Relation of affective disorders and quality of life in the chronic pain of disease Parkinson’s patients

    K. Stepanchenko, A. Jidkova (Kharkiv, Ukraine)

    Objective: To study affective disorders and their impact on the quality of life in patients with PD and chronic pain syndrome. Background: Mechanisms of the…
  • 2022 International Congress

    Inducing motor cortical plasticity in Parkinson’s Disease patients using subthalamic deep brain stimulation and repetitive transcranial magnetic stimulation

    C. Rinchon, C. Gunraj, N. Drummond, T. Hoque, KHS. Chen, R. Chen (Toronto, Canada)

    Objective: To investigate whether motor cortical plasticity can be induced in Parkinson’s disease (PD) patients by pairing subthalamic deep brain stimulation (STN-DBS) and repetitive transcranial…
  • 2022 International Congress

    Clinical phenotype of non-manifesting carriers of mutations in the GBA and LRRK2 genes

    N. Omer, N. Giladi, A. Bar-Shira, M. Gana-Weisz, O. Goldstein, O. Asias, J. Shirvan, J. Cedarbaum, M. Kestenbaum, A. Orr-Urtreger, R. Alcalay, A. Mirelman, A. Thaler (Tel-Aviv, Israel)

    Objective: To explore the influence of carrying mutations in both the GBA and LRRK2 genes (dual mutation carriers) on risk for future development of Parkinson's…
  • 2022 International Congress

    Outcomes after Deep Brain Stimulation (DBS) surgery in patients with young-onset Parkinson’s disease

    L. Jackson, B. Klassen, K. Lee, K. Miller, A. Hassan, R. Savica (Rochester, USA)

    Objective: To assess outcomes after deep brain stimulation (DBS) in patient with young-onset Parkinson’s disease (PD). Background: DBS is a surgical procedure which effectively treats…
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