α-synuclein expression is not mediated by β2-adrenoreceptor modulation in human dopaminergic cells
Objective: Modulation of the β2-adrenoreceptor (also called the β2-adrenergic receptor or β2-adrenoceptor) has been reported to regulate SNCA expression. We sought to determine the expression…Long-term real-world effectiveness of carbidopa/levodopa enteral suspension after 36 months of treatment initiation: Final results from PROviDE study
Objective: To examine the real-world long-term effectiveness of carbidopa/levodopa enteral suspension (CLES) on off time and other patient reported outcomes (PROs) among advanced Parkinson’s disease…Compensation strategies for gait impairment in Parkinson’s disease: a survey among 4,324 patients
Objective: The aim of this study was threefold: (1) to evaluate patients’ awareness and use of various compensation categories for gait impairments in PD; (2)…The pandemic stress impact on disease progression in COVID-19 seronegative patients with idiopathic Parkinson’s Disease.
Objective: To investigate the impact of chronic stress (CS) induced by the present pandemic on the progression rates of motor and cognitive impairment, on neuro-inflammatory…The PRIME Qual study protocol: A qualitative exploration of the experiences of patients, caregivers/families and hospital/intervention staff of the PRIME Randomised Controlled Trial
Objective: This qualitative study seeks to understand how a new model of care influences a person with Parkinson’s ability to stay well physically, maintain their…Subjective cognitive complaints assessed with the cognitive domain of the Non-Motor Symptoms Scale predict longitudinal cognitive trajectory in people with Parkinson’s disease with normal cognition
Objective: To investigate whether subjective cognitive complaints assessed by the Non-Motor Symptoms Scale (NMSS) are predictive of longitudinal cognitive trajectories in cognitively intact people with…Emotional and cognitive information processing in obstacle negotiation in patient with Parkinson’s disease and freezing
Objective: We used emotional (images from the International Affective Picture System - IAPS)1 and cognitive inputs(visual perturbation in a stepping-over-the-obstacle task) with the aim to…THE ABILITY OF PATIENTS WITH PARKINSON’S DISEASE TO RECOGNIZE MASKED FACES DURING COVID-19 PANDEMIC
Objective: This study aims to evaluate the effect of using masks on face recognition ability in Patients with Parkinson’s disease (PwP). Background: Patients with Parkinson’s…Novel PLA2G6 Mutation Presenting as Early-Onset Parkinson’s Disease
Objective: To report a case of a novel mutation in the PLA2G6 gene resulting in early-onset Parkinson’s Disease. Background: The phospholipase A2 group VI (PLA2G6)…Ultrastructural Characterization of Monocytes in Parkinson’s Disease and GBA mutations
Objective: To identify morphological changes in circulating CD14+ monocytes in manifesting and non-manifesting carriers of mutations of the GBA gene and Parkinson’s disease (PD). Background: Mutations of…
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