Beyond the “best contact”: correlation of ai-guided dbs contact distribution and subthalamic nucleus beta physiology in parkinson’s disease patients
Objective: We hypothesized that optimal stimulation setting may involve a muti-contact configuration rather than a single contact with the largest therapeutic window (TW). We aimed…Psychosis in Parkinson’s Disease Patients Treated with Continuous Subcutaneous Foslevodopa/Foscarbidopa: A Real-World Observational Study.
Objective: To assess the incidence and timing of psychosis (hallucinations and delusions) in Parkinson’s disease patients receiving continuous subcutaneous infusion of foslevodopa/foscarbidopa (CSFLI). Background: CSFLI…DTI-Based Comparative Analysis of Microstructural Alterations in Parkinson Disease and Atypical Parkinsonism
Objective: Diffusion tensor imaging (DTI) holds promising potential for investigating pathological changes in white matter (WM). In recent years, numerous studies worldwide have demonstrated that…Establishing the Ukrainian Parkinson’s Disease Cohort within GP2: Early Results from the UPGRADE-PD Initiative
Objective: To describe the early establishment and recruitment outcomes of the Ukrainian Parkinson’s disease cohort within the Global Parkinson’s Genetics Program (GP2). Background: Eastern European…Shared and Sex-Specific Genetic Risk for Parkinson’s Disease Across European Populations
Objective: To investigate sex-specific autosomal genetic factors associated with PD risk. Background: Parkinson’s disease (PD) affects females and males differently, with differences in prevalence, clinical…Seven-Year Outcome of Focused Ultrasound Thalamotomy in Tremor Dominant Parkinson’s Disease Patients
Objective: To assess 7-year outcomes of unilateral MRI-guided focused ultrasound (MRgFUS) ventral intermediate nucleus thalamotomy in tremor-dominant Parkinson’s disease (TDPD) patients with levodopa-unresponsive tremor, and…Deep Brain Stimulation (DBS) For Parkinson’s Disease (PD) Patients Carrying The GBA Gene Variant: Greater-Than-Expected Benefits, Similar Cognitive Decline, But Caution Is Advised Regarding Anxiety And Depression.
Objective: To describe the motor and non-motor response in PD Patients Carrying The GBA Gene Variant under treatment with DBS Background: Parkinson's disease (PD) patients carrying…The Transcriptomic, Neurotransmitter, and Cell Type Signatures Underlying Pure Fatigue in Early-stage Parkinson’s Disease
Objective: This study elucidates spatiotemporal functional connectivity of pure fatigue in early Parkinson’s disease (PD) and uncovering underlying gene expression profiles. Background: Fatigue is a…Nutritional Status as a Modifiable Determinant of Clinical Outcomes in Parkinson’s Disease: A 12-Month Longitudinal Study in Patients Treated with DBS and L-Dopa
Objective: To analyze longitudinal changes in nutritional status in Parkinson’s disease (PD) patients treated with deep brain stimulation (DBS), compared with pharmacological therapy (L-dopa) and to…Visualization of Small Brainstem Nuclei With the Ultra-High Performance NeuroEXPLORER PET Camera: a Comparison Study Using 18F-AV133
Objective: To compare the performance of 18F-AV133 between NeuroEXPLORER (NX) and standard resolution Siemens Biography (mCT) positron emission tomography (PET) cameras in people with Parkinson's…
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