Funding and Sustainability Challenges in Multi-Arm Multi-Stage Clinical Trials in Parkinson Disease
Objective: The Edmond J Safra Accelerating Clinical Trials in Parkinson Disease (PD) initiative (EJS ACT-PD) aims to accelerate the identification of disease modifying treatment for…Continuous subcutaneous apomorphine infusion for the management of Parkinson’s disease at the end-of-life
Objective: To describe the benefit of continuous subcutaneous apomorphine infusion (CSAI) for terminal care management in 7 PD patients. Background: There are currently no recommendations…WATCH-PD: Detecting Early-Stage PD using Feature Engineering and Machine Learning in Remote Sensor-Based Assessments
Objective: Use feature engineering and machine learning to evaluate digital biomarkers of early-stage Parkinson’s disease (PD) in the WATCH-PD study. Background: WATCH-PD – a one-year…Early experience using real-world monitoring to inform Parkinson’s management
Objective: To explore the utility of remote patient monitoring, using a combination of brain sensing and objective outcome measurement, in the management of Parkinson’s disease…Pedunculopontine Nucleus Structural Integrity and Freezing of Gait in Parkinson’s Disease Patients
Objective: We investigated pedunculopontine nucleus (PPN) structural integrity in Parkinson disease (PD) patients with diffusion tensor imaging (DTI) and whether the DTI changes correlate with…Post deep brain stimulation cognitive decline in GBA-related Parkinson’s disease
Objective: Neurocognitive deterioration study in GBA-related Parkinson’s disease (GBA-PD) following Deep Brain stimulation Surgery of the Sub Thalamic Nuclei (STN-DBS) Background: A faster progress of Parkinson’s…Anti-α-synuclein antibody 5G4 differentiates idiopathic REM Sleep Behavior Disorder patients from healthy controls in skin biopsies
Objective: The aim of our study was to assess α-synuclein (α-syn) staining using the 5G4 antibody in skin samples of patients with idiopathic REM Sleep…Genetic determinants of early motor progression in Parkinson’s cohorts
Objective: To determine the genetic determinants of motor progression in Parkinson disease (PD) using genome-wide analysis correlated with the MDS-UPDRS Part III motor scale. Background:…Distribution of rapid eye movement (REM) sleep without atonia (RWA) across the REM cycles.
Objective: This study aimed to evaluate whether rapid eye movement )REM( sleep without atonia )RWA( is similar throughout multiple REM cycles during one night. Background:…What research participants want to know: Feedback from participants in an observational study of Parkinson’s disease
Objective: To compare participant feedback regarding clinical assessments, patient-reported outcomes (PROs), and digital technologies provided in individual research reports in an observational study of Parkinson’s…
- « Previous Page
- 1
- …
- 316
- 317
- 318
- 319
- 320
- …
- 436
- Next Page »