Randomized, Placebo-Controlled Single Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of ABBV-0805, an Anti-Alpha-Synuclein Monoclonal Antibody in Healthy Subjects
Objective: To evaluate the safety, tolerability, pharmacokinetics (PK), and immunogenicity of ABBV-0805 following administration of single ascending doses of ABBV-0805, administered as intravenous (IV) infusions…Decreased expression of trace amines receptors on lymphocytes in Parkinson’s disease
Objective: To determine the expression of TAAR1 and TAAR2 mRNA in leukocytes of patients with Parkinson's disease, depending on the stage of the disease and…Potential drug-drug interactions in hospitalized patients with Parkinson’s disease from tertiary center in Serbia
Objective: The aim of this study was to identify predictors of potential drug-drug interactions in patients suffering from Parkinson’s disease.The aim of this study was…Assessment of Fluctuating Parkinson’s Disease with Sensor-Based Home Monitoring-Feasibility Results
Objective: To implement home-based monitoring (HBM) using wearable devices, a smartphone dedicated app and patient reported outcomes in order to provide a more comprehensive picture…Findings from a Community-based LOUD Crowd® Program for People with Parkinson Disease
Objective: SPEAK OUT!® and LOUD Crowd® programs target the communicative functioning of people with Parkinson disease (PD). The current study includes findings from a year-long…Combined Plantar Stimulations Using a Novel Parkinson Shoe benefit Parkinson’s Disease Patients with Unresponsive Freezing of Gait
Objective: To explore the effect of combined vibratory and pressure stimulations in PD patients with unresponsive FOG and develop the innovative PD shoe. Background: Freezing…Levodopa responsive gait dynamics in ON- and OFF-state freezing of gait in Parkinson’s disease
Objective: To determine which spatiotemporal gait parameters respond to levodopa in Parkinson’s patients with levodopa ON- and OFF-state gait freezing. Background: Levodopa-ON-state gait freezing is…EPIDEMIOLOGICAL OVERVIEW OF PARKINSON’S DISEASE IN BRAZIL
Objective: To describe the epidemiological profile in patients hospitalized with Parkinson's Disease in Brazil during the years 2015 to 2020. Background: Parkinson's disease (PD) is…Machine Learning (ML) Prediction of Parkinson’s Disease (PD) Risk and Nigral Neuron Density
Objective: To investigate associations between nigral neuron density and ML-based PD risk prediction. Background: Early identification of persons at high risk for developing PD is…Plasma phosphorylated α-synuclein relates to cognitive impairment in patients with Parkinson’s disease
Objective: To investigate whether plasma phosphorylated α-synuclein (p-syn) were associated with cognitive function in Parkinson’s disease (PD). Background: Parkinson’s disease (PD) is the second most…