Model Innovation in Parkinson’s disease drug development: linking Quantitative Systems Pharmacology to the patient voice
Objective: There is a growing sense of urgency to integrate the voice of the patient in drug development in Parkinson’s disease (PD). Public private partnerships…Direct Costs of patients with Parkinson’s Disease in a region of the Brazilian Amazon
Objective: To evaluate the perception of the annual direct costs (medications, medical appointments, rehabilitation, transportation) associated with the treatment for patients with PD in the…Trunk postural control in seated position on a prototype of unstable chair and the interference of cognitive and motor tasks in individuals with Parkinson disease
Objective: To analyze trunk balance control of individuals with Parkinson disease (PD) in seated position and compare the control position with motor and cognitive tasks.…The EPSILON (Early ParkinSon wIth L-dopa/DDCi and OpicapoNe) study in early Parkinson’s disease: design and rationale of a phase III, double-blind, randomized, placebo-controlled study
Objective: This study aims to explore the potential of opicapone (OPC) to enhance the clinical benefit of levodopa (L-dopa)/dopa decarboxylase inhibitor (DDCi) in patients with…CVT-301 (levodopa inhalation powder): meta-analysis of safety in patients with Parkinson’s disease (PD)
Objective: Safety results from a phase 3, double-blind study of CVT-301 in patients with PD were combined with results from a 4-week, phase 2b, double-blind,…Therapy to Reduce dementia risk In Parkinson’s disease (TRIP): Proof-of-concept trial
Objective: The TRIP proof-of-concept study examines functioning of the hippocampal DG/CA3 subregion as a biomarker and therapeutic target for memory impairment in Parkinson’s Disease (PD).…The effect of medical xenon on patients with advanced stages of the Parkinson’s disease with motor fluctuations
Objective: The aim of the study to increase the effectiveness of pharmacotherapy in patients with advanced stages of Parkinson's disease (PD) with motor fluctuations, using…Survey-Based study of marijuana used in Parkinson’s Disease patients
Objective: A survey based assessment of marijuana use in patients with Parkinson’s disease. Background: Due to marijuana’s controlled status little quality research and no clear…Influence of demographic characteristics on the effectiveness of opicapone in Parkinson’s disease patients with motor fluctuations: findings from the real-world OPTIPARK study
Objective: This post-hoc analysis evaluated the influence of baseline demographic characteristics (i.e., age and gender) on the response to opicapone (OPC) in Parkinson’s disease (PD)…Problems faced by Parkinson’s disease patients during COVID-19 pandemic compulsory lockdown and its management with the help of Telemedicine in a North Indian cohort
Objective: To study problems faced by PD patients during lockdown due lack of healthcare and medication procurement and address such problems using telemedicine via virtual…