Describing Factors Associated with Progression in Parkinson’s Disease: A Retrospective Chart Review
Objective: To describe differences in sociodemographic and clinical profiles between patients with Parkinson’s disease (PD) who remain at Hoehn and Yahr (HY) stage 1–2 up…Responsiveness of a Smartphone-Based Sensor-Derived Composite Endpoint in a Phase 2b Study in Parkinson’s Disease (PD)
Objective: Development of a sensor-derived composite score (CS) for progression of motor symptoms in the LUMA study in PD. Background: LUMA (NCT05348785) is a randomized Phase 2b…Toward a Standardized Measure of Parkinson’s Disease Psychosis: Preliminary Inter-Rater Reliability of the MDS Parkinson’s Disease Psychosis Rating Scale (MDS-PDPRS)
Objective: To evaluate the inter-rater reliability (IRR) of the MDS-PDPRS in a pilot clinimetric cohort. Background: No validated outcome assessment exists to measure the functional…Microglial Inflammatory Signaling Mediates Neuroimmune Dysregulation And Behavioral Dysfunction in A Parkinson’s Disease Model
Objective: To determine whether M1 microglial signaling via FAM19A3, CHI3L1, and VILIP-1 contributes to neuroinflammation, neuronal degeneration, and behavioral dysfunction in a Parkinson’s disease, and…Impact of Hula on Balance Outcomes in Parkinson’s Disease
Objective: This study aims to determine the impact of a 12-week Hula program on balance in patients with Parkinson’s Disease (PD) and to investigate changes…Social Cognition in Patients with Parkinson’s Disease
Objective: We aimed to investigate social cognition in patients with Parkinson's disease (PD) using facial affect tasks of the Florida Affect Battery (FAB). Background: Patients with…Circadian Regulator REV-ERBα Drives Microglial Lipid Metabolic Reprogramming and Cognitive Impairment in Parkinson‘s Disease
Objective: To investigate the mechanisms by which sleep disturbance exacerbates motor and cognitive deficits in Parkinson’s disease (PD), and to determine how alterations in the…Set_my_DBS: Multicenter study for the development of quantitative methods to support the programming of deep brain stimulation systems in patients with Parkinson’s disease.
Objective: To develop quantitative methods to assist clinicians in the programming of DBS systems, while establishing a consortium-based protocol among participating hospitals andcreating a secure…Move-Brain-PD: a Randomized Multicenter Protocol of Remotely Monitored Home-based Aerobic Exercise for Parkinson’s Disease Patients with Mild Cognitive Impairment
Objective: To describe the rationale and design of Move-Brain-PD, a randomized multicenter study evaluating whether remotely monitored home-based aerobic exercise improves cognition and motor symptoms…Clinical Profile of Early-Onset Parkinson’s Disease in a Tertiary Hospital in Oman
Objective: To investigate the prevalence of early-onset Parkinson’s disease (EOPD) among patients attending the movement disorder clinic at a tertiary hospital in Oman. We also…
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