Deep brain stimulation contact selection using Neurophysiology and Artificial intelligence
Objective: To develop a machine learning (ML) algorithm capable of predicting the optimal deep brain stimulation (DBS) contact based on neurophysiology. Background: DBS is an…The impact of long-term continuous subcutaneous apomorphine infusion on the reduction of remaining medications in levodopa equivalent dosage and on increasing plasma vitamin B12 levels in patients with advanced Parkinson’s disease
Objective: To evaluate the plasma levels of vitamin B and homocysteine among 28 advanced PD patients with motor complications before and after continued used of…Pathological Mechanisms Associated with Atrazine-Induced Parkinson’s Disease Pathogenesis in Rat Model: The Rescue Role of Myricetin
Objective: This study aimed at investigating the mechanisms involved in the pathogenesis of Parkinson’s Disease in atrazine rat model of Parkinson’s Disease and the neuroprotective…Discriminating alpha-synuclein strains in Parkinson’s disease
Objective: To evaluate possible differences in the biological properties of alpha-synuclein fibrils derived from different patients with Parkinson's disease. Background: Parkinson’s disease (PD) is a…The role of extracellular vesicles in the progression of Parkinson’s disease
Objective: The objective of this study is to investigate the role of extracellular vesicles (EVs) in the progression of Parkinson’s disease Background: Parkinson’s disease (PD)…White matter abnormalities in motor subtypes of Parkinson’s disease
Objective: To evaluate white matter microstructural integrity in Tremor dominant Parkinson’s disease (TDPD) and postural instability and gait disturbance (PIGD) subtypes of PD to ascertain…Habenular Structural Connectivity Changes in Parkinson’s Disease: A 7T MRI Study
Objective: To assess if the structural connectivity of habenula (Hb) differs between Parkinson’s disease (PD) patients and healthy controls (HCs). Background: PD is marked by…Severity of Motor Symptoms Correlates with Asymmetric Changes in Globus Pallidus Internus and Caudate Nuclei in Parkinson’s Disease
Objective: Explore the relationship between MDS-UPDRS motor sub-scores (MDS-UPDRS-III) and cerebral perfusion in different Regions of Interest (ROI) in patients with Parkinson’s disease (PwP). Background:…Enlarged Perivascular Spaces in the Temporal Lobe as a Predictor for Incident Dementia in Parkinson’s Disease
Objective: To evaluate the whether regional burden of enlarged perivascular space (EPVS) hold prognostic value in predicting the dementia conversion in Parkinson's disease (PD). Background:…Deep learning-based Prediction of Gait Dysfunction in Parkinson’s Disease using Quantitative Diffusion MRI from Brain Network Regions of Interest
Objective: Compare the performance of two deep learning models trained on quantitative diffusion measurements from brain network ROIs in the prediction of gait dysfunction in…
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