Disrupted Sleep Circadian Rhythms and Brain Disorders: A Large Prospective Cohort Study
Objective: Disrupted sleep circadian rhythms have been linked to increased risks of dementia and mental health, but their associations with other brain disorders were underestimated.…Prevalence of Parkinson’s Disease and Possible Parkinsonian Syndrome in Gaucher Disease: Data From the ICGG Gaucher Registry
Objective: To estimate the age-specific risk of Parkinson’s disease (PD) and possible parkinsonian syndrome (pPS) in Gaucher disease (GD) based on registry data. Background: While…Exploring MAPT Haplotypes in Parkinson’s Disease in a Diverse Cohort: Insights from the Global Parkinson’s Genetics Program
Objective: To assess the frequency of H1/H2 haplotypes in MAPT across diverse ancestries from the Global Parkinson’s Genetics Program(GP2) and investigate their association with Parkinson's…Studying monogenic Parkinson’s disease by building a global cohort of mutation carriers
Objective: ObjectiveTo build a multi-ancestry cohort of individuals with pathogenic variants in genes known to cause Parkinson’s disease (PD) to study monogenic PD at a…Clinico-genetic profile of five patients with PARK-PINK1: A case series from India
Objective: The aim of our study is to describe the clinical features and genetic profile of patients of PARK-PINK1 and to draw correlation with genetic…A Rare Case of Parkinson’ s Disease Associated With Heterozygous ATP13A2 Gene Mutation: What If There Are No Atypical Features with a Later Onset?
Objective: Autosomal recessive mutations in ATP13A2 gene is a rare cause of levodopa-responsive parkinsonism with atypical features of supranuclear gaze palsy, spasticity, dystonia, dementia, myoclonus,…Transcranial Direct Current Stimulation for Freezing of Gait in Parkinson’s Disease
Objective: To investigate the impact of anodal transcranial direct current stimulation (tDCS) on freezing of gait (FOG) among individuals diagnosed with Parkinson’s disease (PD). Background:…V-ATPase subunit V1G1 overexpression conferred the mice neuroprotection during MPTP exposure
Objective: Elucidating the role of lysosomal dysfunction due to altered stability and expression levels of V-type proton ATPase subunit G (V1G1) in the degradation and…Sexual Dimorphism in Clinical Subtypes, Biomarkers and Disease Progression of Parkinson’s Disease
Objective: To investigate differences in clinical subtypes, biomarkers, and course of progression in Parkinson’s disease (PD) between the two biological sexes. Background: PD is a…Comprehensive Strategy for Increasing Clinical Research Participation of Black and Hispanic Patients with Parkinsonism
Objective: To implement and test a multidimensional strategy for increasing racial and ethnic diversity in parkinsonism research. Background: Diversity in research participation is critical for…
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