Alpha-Synuclein Amplification Assays Utilizing Real-Time Quaking-Induced Conversion (RT-QuIC) from Non-Invasive Saliva as a Novel Diagnostic Tool for Patients with Parkinson’s Disease
Objective: The main objective is to evaluate the sensitivity of aSyn-RT-QuIC in diagnosing Parkinson's Disease (PD) from non-invasive saliva. The results will be corroborated in…Dried Plasma Spot Cards for Measurement of Neurofilament Light Chain
Objective: Evaluate measurement of neurofilament light chain (NfL) in dried plasma spot cards, and to compare these to measurements using more invasive and in person…Cognitive and Motor Wobbling in Isolated RBD: A Multicentric Study by the International RBD Study Group (IRBDSG)
Objective: To define and characterize clinically fluctuating transition phases from isolated RBD (iRBD) to overt alpha-synucleinopathy. Background: Patients with iRBD often develop motor and non-motor…Novel Usage of Alpha Synuclein as a Biomarker for Screening Parkinson’s disease at Komfo Anokye Teaching Hospital in Ghana
Objective: This study aimed to assess the use of alpha-synuclein as a biomarker for PD screening and investigate its correlation with disease severity. Background: The…Neural Signatures of Hallucination Emergence in Dementia with Lewy Bodies
Objective: REM sleep behavior disorder (RBD) is a prodromal state for alpha-synucleinopathy. Here, we present a behavioral marker for hallucination propensity that distinguishes Dementia with…Comparative Analysis of MoCA Scores Between Latin American Latinos and White Patients with Parkinson’s Disease
Objective: The study objectives were to 1) characterize scores on the Montreal Cognitive Assessment (MoCA) in patients with Parkinson’s disease (PD) from Latin America, 2)…Modeling Dementia in Patients with Parkinson’s Disease Years After DBS
Objective: The objective of this study is to identify pre-operative cognitive characteristics of patients who are candidates for deep brain stimulation surgery that may contribute…Comparison of 3 Tests for Subjective Cognitive Complaints in Early Parkinson’s Disease
Objective: To compare 3 scales which have been used in literature to determine subjective cognitive complaints (SCC) in Parkinson’s disease (PD) and explore their relationship…Probiotic Treatment for Depression and Associated Mood Disorders in Parkinson’s Disease – A Randomized, Placebo-Controlled Trial (Short Title: ProD)
Objective: Objective: To assess the impact of probiotic supplementation on depression symptoms and the gut microbiome in people living with Parkinson’s disease (PwPD). Background: Background:…Distinguishing Functional and Essential Tremor from Tremor in Parkinson’s Disease using an objective comprehensive Motor Symptom Assessment Device
Objective: Our main aims were to 1) increase diagnostic accuracy and 2) reduce the time needed to reach the correct diagnosis in three disorders with…
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