Early longitudinal changes in non-motor symptoms and routine health checkup parameters around the emergence of prodromal features of Lewy body disease
Objective: To investigate biological changes in early prodromal Lewy body disease (LBD) using routine health checkup data. Background: Various prodromal symptoms appear years before LBD…Deep brain stimulation effects on Parkinson’s disease patients with orthostatic hypotension
Objective: To evaluate orthostatic blood pressure changes before and after subthalamic deep brain stimulation (STN-DBS) and to determine whether outcomes were related to DBS therapy…A Rare Case of PLA2G6 Gene Related Early-Onset Dystonia-Parkinsonism; What Not to Miss Clinically and Radiologically
Objective: PLA2G6-associated neurodegeneration (PLAN) is a rare form of neurodegeneration with brain iron accumulation (NBIA) leading to heterogeneous clinical manifestation including infantile neuroaxonal dystrophy, atypical…The Prevalence of Parkinson’s Disease in Kilifi County, Kenya: A ‘Transforming Parkinson’s Care in Africa’ (TraPCAf) study
Objective: We aimed to determine the prevalence of PD in Kilifi County, Kenya within the Kilifi Health and Demographic Surveillance System and evaluate the performance…Hybrid deep brain stimulation conversion using the S8 adaptor in Parkinson’s disease
Objective: To evaluate the feasibility and short-term outcomes of hybrid deep brain stimulation (DBS) conversion using the S8 adaptor in Parkinson’s disease (PD). Background: DBS…Restoring the Axis: Efficacy of Fecal Microbiota Transplantation (FMT) on Motor and Non-Motor Symptoms in Parkinson’s Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials (2023–2025)
Objective: To methodically assess the safety and effectiveness of fecal microbiota transplantation (FMT) in comparison to a placebo for Parkinson's disease (PD) patients' motor and…Non-Motor Symptom Burden as a Key Determinant of Disease Clustering in Parkinson’s Disease
Objective: To evaluate how non-motor symptoms drive the classification of Parkinson’s disease (PD) patients beyond standard motor subtyping. Background: While motor symptoms are the hallmark…A Pilot Study of Phosphorylated Alpha-Synuclein Detection and Quantitation from Routine Colonic Biopsies in Patients with Parkinson’s disease
Objective: To develop a novel method for the detection of P-SYN within superficial colon biopsies that can be obtained during routine colonoscopy. Background: Parkinson’s disease…American Parkinson Disease Association Outreach to Mandarin-Speaking Communities in the United States
Objective: To describe the American Parkinson Disease Association (APDA)’s growing engagement with Mandarin-speaking communities in the US and share lessons from outreach efforts that combine translated…The Effect of Scapular Dysfunction on Dynamic Balance in Patients with Parkinson’s Disease
Objective: To investigate the effect of scapular dysfunction on dynamic balance in patients with Parkinson’s disease (PD). Background: Posture and balance are influenced by voluntary…
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