Apomorphine Sublingual Film for “OFF” Episodes in Parkinson’s Disease: Analysis of Baseline Factors
Objective: Determine if baseline factors are associated with the apomorphine sublingual film (APL) dose required to achieve FULL “ON.” Background: APL is approved for the…A New Phase of the Parkinson’s Outcomes Project Registry Study
Objective: Objective: To provide an update on the Parkinson’s Outcomes Project, a longitudinal study measuring outcomes among people with Parkinson’s disease (PwP). Background: Background: Data…Apomorphine Sublingual Film for “OFF” Episodes in Parkinson’s Disease: Characterization of Acute Nausea During Dose Titration
Objective: Characterize acute episodes of nausea experienced by patients with Parkinson’s disease (PD) receiving apomorphine sublingual film (APL) for the on-demand treatment of “OFF” episodes.…A phase 2b randomized, double-blind, placebo-controlled study of suvecaltamide in the treatment of adults with moderate to severe essential tremor: study design and methodology
Objective: Evaluate the efficacy and safety of JZP385 (formerly CX-8998), a highly selective T-type calcium channel modulator, for symptomatic control of moderate to severe essential…Long-Term Safety and Efficacy of Apomorphine Sublingual Film for “OFF” Episodes in Parkinson’s Disease: Europe vs North America
Objective: Evaluate long-term safety (LTS), tolerability, and efficacy of apomorphine sublingual film (APL) for on-demand treatment of “OFF” episodes in patients with Parkinson’s disease (PD)…A Phase 2 Randomized Controlled Trial Repurposing Ambroxol as a Disease Modifying Treatment for Parkinson’s Disease Dementia.
Objective: Currently there are no disease-treatments for Synucleinopathies including Parkinson’s disease dementia (PDD). Our objective is to use Ambroxol to target GBA/Glucocerebrosidase to treat PDD.…Indirect Comparison of Apomorphine Sublingual Film Versus Levodopa Inhalation Powder for “OFF” Episodes in Parkinson’s Disease
Objective: Conduct a matching-adjusted indirect comparison (MAIC) of the efficacy of apomorphine sublingual film (APL) vs levodopa inhalation powder (CVT-301) for “OFF” episodes in Parkinson’s…SB-0107, a drug repurposing opportunity identified through machine learning, shows the potential to treat Parkinson’s disease motor disability and levodopa-induced dyskinesia in rat and primate models
Objective: To characterize the effects of a computationally identified small molecule in rat and primate models of Parkinson’s disease-associated motor deficits and treatment-associated complications. Background:…Safety, tolerability and CNS effects after single and multiple doses of β-agonists in healthy volunteers and patients with Parkinson’s disease
Objective: This study aimed to assess the effects of β-agonists on central nervous system (CNS) functioning in healthy volunteers and patients with Parkinson’s disease. Background:…Is past use of statins associated with lower incidence of Parkinson’s disease?
Objective: To examine the relation of past exposure to statins with Parkinson’s disease (PD) incidence. Background: Drug repurposing has recently emerged as a promising approach…
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