MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Pharmacotherapy"

  • 2024 International Congress

    Recruitment of Ethnoracially Diverse Participants for Disease-Modifying Drug Trials in Parkinson’s Disease: Are We Doing It Right? A Systematic Review and Meta-Analysis.

    F. Reis Rodrigues, E. Pasqualotto, G. Ribeiro, J. M. Couto, E. Bayram, M. Ushe, D. Di Luca (Vicosa, Brazil)

    Objective: To perform a systematic review and meta-analysis on recruitment of people with Parkinson’s disease (PwP, PD) from different ethnic and racial groups in disease-modifying…
  • 2024 International Congress

    Clinical characteristics associated with early discontinuation of Levodopa-Carbidopa Intestinal Gel infusion in patients with advanced Parkinson Disease.

    D. Rivero-Rodríguez, M. Morales-Casado, G. Tabar-Comellas, A. Diezma-Martín, P. Quintana-Castro, M. Ennazeh, N. López-Ariztegui (Toledo, Spain)

    Objective: To determine the clinical characteristics associated with early withdrawal of Levodopa-Carbidopa Intestinal Gel infusion (LCIG) in patients with advanced Parkinson´s Disease (APD) Background: LCIG…
  • 2024 International Congress

    Oro-facial Dyskinesia and akathisia following Treatment by Olanzapine

    S. Saaf, S. Lhassani, Z. El Yacoubi, Y. Mimouni, M. El Azhari, L. Kazzoul, J. Aasfara, H. Ouhabi, A. Hazim (Casablanca, Morocco)

    Objective: To report the case of a pharmaco-induced oro-facial dyskinesia and akathisia. Background: Dyskinesia is a hyperkinetic, disorganized, involuntary movement disorder that can either be…
  • 2024 International Congress

    Opicapone Reduces Homocysteine Levels in Patients with Parkinson’s Disease Treated with Levodopa Gel Infusion

    M. Minar, I. Straka, Z. Kosutzka, Z. Andre (Bratislava, Slovakia)

    Objective: Our study aims to assess the effect of an add-on treatment with catechol-O-methyl transferase (COMT) inhibitor, opicapone, on the plasmatic levels of homocysteine (HCY)…
  • 2024 International Congress

    Changes in Parkinson’s Disease and Parkinsonian Syndromes A Comparative Retrospective Study in Kyrgyzstan

    S. Medetbekova, B. Nurbekova (Bishkek, Kyrgyzstan)

    Objective: This study compares Parkinson's disease (PD) and parkinsonian syndromes (PS) in patients at a Kyrgyzstan university hospital. It analyzes data from 2016-2017 [1] and…
  • 2024 International Congress

    Buspirone/zolmitriptan combination exerts synergistic reduction in dyskinesia without worsening Parkinson disease motor symptomatology

    P. Lewitt, G. Stebbins, K. Christensen, M. Thomsen, R. Tan, A. Pretorius (Detroit, USA)

    Objective: Levodopa-induced dyskinesias (LID) may be amenable to interventions with striatal serotonergic receptors. Preclinical evidence suggests that co-administration of serotonergic agonists with selective receptor properties…
  • 2023 International Congress

    Changes in artistic style and Parkinson’s Disease

    AM. Diezma Martín, G. Tabar Comellas, MI. Morales-Casado, DD. Garcia Melendez, JW. Ruiz Gómez, P. Quintana Castro, M. Ennazeh Elkhaili, D. Rivero Rodríguez, N. López Ariztegui (Toledo, Spain)

    Objective: We present a Parkinson’s disease (PD) patient in whom dopamine agonists produced a dramatic change in her art style and production, and the subsequent…
  • 2023 International Congress

    15-year effects of initiating treatment for Parkinson’s disease with dopamine agonists or monoamine oxidase B inhibitors compared with levodopa: final results of PD MED early disease randomisation

    C. Clarke, C. Rick, S. Patel, R. Wooley, N. Rowland, J. Futterer, R. Ottridge, C. Jenkinson, R. Gray (Birmingham, United Kingdom)

    Objective: PD MED EARLY is a large, pragmatic trial aiming to determine which class of drug as initial treatment provides the most effective long-term control…
  • 2023 International Congress

    A phase 2 randomized, double-blind, placebo-controlled trial of Ambroxol as a disease-modifying treatment for Parkinson’s disease dementia.

    S. Pasternak, C. Silveira, K. Coleman, R. Garcia, J. Wells, M. Borrie, P. Macdonald, R. Bartha, M. Jenkins, S. Morrow, D. Mendonca, G. Zou, E. Finger, T. Rupar, R. Tirona, M. Jog (London, Canada)

    Objective: To evaluate the safety and tolerability of repurposing Ambroxol as a disease modifying treatment for Parkinson’s Disease Dementia (PDD). Background: Carrying a mutation in…
  • 2023 International Congress

    Long-term effectiveness of adjuvant treatment with catechol-o-methyltransferase or monoamine oxidase B inhibitors compared with dopamine agonists in Parkinson’s disease uncontrolled by levodopa: final results of the PD MED LATER randomized clinical trial

    C. Clarke, C. Rick, S. Patel, R. Wooley, N. Rowland, J. Futterer, R. Ottridge, C. Jenkinson, R. Gray (Birmingham, United Kingdom)

    Objective: PD MED LATER is a large, pragmatic trial aiming to determine which class of drug when added to levodopa provides the most effective control…
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