MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Positron emission tomography(PET)"

  • 2025 International Congress

    Striatal Dysfunction in Parkinson’s Disease Progression: A 18F-9-fluoropropyl-(+)-dihydrotetrabenazine(18F-AV133) PET Study

    X. Liu, G. Tamagnan, H. Qiao, J. Lu, C. Zhang, S. Liu (Beijing, China)

    Objective: To investigate the patterns of striatal 18F-AV133 uptake in relation to disease progression across different stages of PD and to examine its relationship with…
  • 2025 International Congress

    Comparison of Microglial PET Imaging in Parkinson’s Disease, RBD, and Controls with a CSF1R and TSPO Ligand.

    K. Mills, I. Cheong, Y. Du, J. Coughlin, A. Horti, C. Motley, R. Dannals, W. Lesniak, T. Dawson, M. Pomper (Baltimore, USA)

    Objective: To compare regional binding patterns of microglial PET radioligands: [11C]DPA-713, a TSPO ligand, and [11C]CPPC1, a CSF1R ligand  in people with Parkinson’s disease (PD).…
  • 2025 International Congress

    Dopaminergic and Synaptic Alterations in SWEDD: Insights from [¹⁸F] FE-PE2I and [¹¹C] UCB-J PET Imaging

    F. Ebrahimian Sadabad, T. Volpi, P. Honhar, L. Colon, S. Tinaz, M. Naganawa, M. Dias, G. Angarita, R. Comley, R. Carson, S. Finnema, D. Matuskey (Tallahassee, USA)

    Objective: To investigate dopaminergic and synaptic density in SWEDD patients compared to idiopathic Parkinson’s disease (IPD) and healthy controls (HCs). Background: Scans Without Evidence of…
  • 2025 International Congress

    Alterations in Basal Ganglia Synaptic Density and Thalamic Gray Matter Volume are associated with Motor Signs in Late Life Depression: an 11C-UCB-J PET/MR study.

    M. van Cauwenberge, T. Vande Casteele, M. Laroy, K. Vansteelandt, K. van Laere, J. Vanden Stock, F. Bouckaert, L. Emsell, M. Vandenbulcke (Leuven, Belgium)

    Objective: To investigate differences in the association of motor signs with synaptic density, gray matter volume and white matter lesion volume in patients with late…
  • 2025 International Congress

    Functional Segregation in Parkinson’s Disease

    DN. Su, J. Hanania, A. Pavel, M. Matarazzo, J. Mckenzie, J. Cheng, N. Vafai, S. Dhaliwal, V. Sossi, A. Stoessl (Beijing, China)

    Objective: We assessed patterns of dopamine (DA) release and striatal activation induced by behavioural tasks involving corticostriatal loops in Parkinson’s disease (PD) and healthy control…
  • 2025 International Congress

    Longitudinal FDG-PET Study of Metabolic Trajectories and Connectivity Alterations in Multiple System Atrophy

    Y. Zhao, H. Lin, X. Li, F. Liu, J. Wang (Shanghai, China)

    Objective: 本研究使用 FDG-PET 探索 MSA 中葡萄糖代谢和网络连接的纵向变化,以辅助早期诊断和监测疾病进展。 Background: Multiple system atrophy (MSA) is a rapidly progressive neurodegenerative disease with distinct metabolic patterns in its parkinsonian (MSA-P)…
  • 2025 International Congress

    Clinical Profile and 18F -Fluorodopa Positron Emission Tomography (18F -DOPA PET) Findings in a Movement Disorder Clinic Patient Cohort

    S. Yellaturi, M. Prabhu, A. Behera, S. Pandey (Faridabad, India)

    Objective: This study aimed to evaluate the utility of 18F -DOPA PET in patients with diagnostic uncertainty at our movement disorder clinic in India. Background:…
  • 2025 International Congress

    PET and Clinical Evidence for Neuroprotective Effects of KM-819 on MSA

    C. Lee, C. Barlow, E. Kim, D. Kim, D. Doudet, J. Ko, M. Goh (Seongnam-si, Gyeonggi-do, Republic of Korea)

    Objective: To assess the effect of KM-819 on the progression of multiple system atrophy (MSA). Background: Parkinson’s brain is associated with increased expression of the…
  • 2025 International Congress

    Cerebral Glucose Metabolic Features of GBA-Parkinson’s Disease as a window into cognitive impairment

    P. Mitrotti, R. Calabrese, M. Picascia, L. Gallo, R. Malito, A. Panzacchi, C. Galandra, M. Todisco, R. Zangaglia, D. Perani, A. Chiti, EM. Valente, C. Tassorelli, S. Camminiti, M. Avenali (Pavia, Italy)

    Objective: to investigate cerebral glucose metabolism via fluorodeoxyglucose positron emission tomography (FDG-PET) and its correlation to clinical features in Parkinson’s disease (PD) patients with GBA1…
  • 2025 International Congress

    Topographical heterogeneity of cholinergic system status in Multiple System Atrophy: A series report

    A. Narkis, G. Carli, J. Barr, R. Vangel, C. Spears, R. Albin, P. Kanel, N. Bohnen (Ann Arbor, USA)

    Objective: To characterize individual-level topographical patterns of cholinergic upregulation and downregulation in Multiple System Atrophy (MSA) using a whole brain voxel-wise approach. Background: MSA is…
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