MRI morphometry and regional hypometabolism in the clinical predominance-types of Progressive Supranuclear Palsy
Objective: To compare brain MRI morphometry and regional hypometabolism among the clinical predominance-types of Progressive Supranuclear Palsy. Background: Recently, MDS-PSP criteria for the clinical diagnosis…Asymmetric synaptic density and glucose consumption in subjects with non-demented Parkinson’s Disease, as measured with [11C]UCB-J and [18F]FDG PET.
Objective: The objective of this study was to investigate asymmetric synaptic density and glucose consumption in moderate-stage non demented PD patients and the association between…Association of Increased Frontal White Matter A2A Receptor Availability with Decreased Frontal Gray Matter Volume in Patients with Parkinson’s Disease
Objective: We sought to investigate in vivo changes in A2A receptor availability in cerebral white matter of PD patients and its association with gray matter…In vivo synaptic density in parkinsonism
Objective: To provide first evidence of in vivo binding properties of the [18F]SynVesT-1 tracer (aka [18F]-SDM-8) for the quantification of synaptic density loss in a…Brain effects of high-intensity exercise on the dopamine system in individuals with Parkinson’s disease
Objective: We used PET imaging with 18F-FE-PE2I to quantify dopamine transporter availability and neuromelanin (NM)-MRI to measure the NM content in the substantia nigra (SN)…Longitudinal combined 11C UCB J and 18F FE PE2I PET imaging of presynaptic terminal loss in early Parkinson’s disease.
Objective: To longitudinally assess presynaptic terminal loss in vivo over a 2-year period in people with early Parkinson’s disease (PD). Background: Imaging tools that allow…Distinct amyloid-dependent patterns of nigral dopamine depletion in Lewy body diseases
Objective: To investigate the effect of amyloid on striatal 18F-FP-CIT uptake patterns in Lewy body disease (LBD), including Parkinson’s disease (PD) and dementia with Lewy…FDG-PET features of Lewy body dementia among patients with amnestic presentations typical for Alzheimer’s disease
Objective: To better understand the role of FDG-PET for identifying dementia with Lewy bodies (DLB) in the context of Alzheimer’s disease (AD)-like amnestic presentations, we…Multimodal assessment of nigrostriatal degeneration in de novo Parkinson’s disease
Objective: To study nigrostriatal changes with a multifactorial neuroimaging approach in order to further characterize early abnormalities in Parkinson’s Disease (PD). Background: Imaging techniques allow…Effect of exercise on brain metabolism and energetics in PD
Objective: To identity the effect of exercise on brain metabolism and energetics in PD using PET/MR imaging. Background: Aerobic exercise slows PD progression as reflected…
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