Metabolic patterns and neurodegeneration in isolated REM sleep behavior disorder
Objective: To elucidate the role of Parkinson’s disease (PD)-related brain metabolic patterns as a biomarker in isolated rapid-eye-movement sleep behavior disorder (iRBD) for clinical correlation…Longitudinal 18F-PBR06 (TSPO) and Volumetric MR Imaging as Pharmacodynamic Endpoints for MSA – Ongoing Investigator Sponsored Trial of Verdiperstat
Objective: In multiple system atrophy (MSA) patients to: 1) evaluate 18F-PBR06 positron emission tomography (PET) for longitudinal assessment of 18-kilodalton-translocator protein (TSPO) binding; 2) assess…Persistent and efficient transduction of the putamen following gene therapy for aromatic L-amino acid decarboxylase deficiency
Objective: This study aimed to evaluate longitudinal transduction in subcortical regions and transduction of the cortico-putaminal network after putaminal AADC gene therapy. Background: Aromatic L-amino…Language impairment in Corticobasal Syndrome: from clinical phenotype to biomarkers
Objective: To investigate the language impairment profile of patients diagnosed as probable Corticobasal Syndrome (CBS) [1] in light of a multimodal imaging biomarkers analysis, namely…Impulse control disorder and ventral striatum dopamine D3 receptor availability in Parkinson’s disease
Objective: To investigate the relationship between ventral striatum D3 dopamine receptor availability and severity of impulse control disorder (ICD) in Parkinson’s disease (PD). Background: Reduced…In vivo imaging of presynaptic terminal loss in early Parkinson’s disease
Objective: To determine the magnitude and anatomical extent of presynaptic terminal damage in early Parkinson’s disease (PD) in vivo, we performed a PET study with…Levodopa-induced dyskinesias and substantia nigra dopamine D3 receptor availability in Parkinson’s disease
Objective: To investigate with PET and the radioligand [11C]PHNO whether levodopa-induced dyskinesias in Parkinson disease (PD) are associated with dopamine-D3 receptor (D3R) overexpression in substantia nigra…Correlation between location of active contacts and weight gain after subthalamic nucleus deep brain stimulation in Parkinson’s disease
Objective: Objective: The aim of this study was to evaluate the correlation between the location of active contacts and weight gain after subthalamic nucleus deep…Mechanisms of chronic neuroleptic-induced parkinsonism examined with positron emission tomography
Objective: To investigate the cause of chronic neuroleptic drug-induced parkinsonism (NIP) through examination of the profile of striatal monoaminergic nerve terminal density using positron emission…Dopaminergic denervation in de-novo Parkinson’s disease. Does functional somatotopy plays a role?
Objective: To clarify how dopaminergic denervation occurs along the dorsoventral axis of the posterior putamen in the earliest stages of PD. Background: Dopamine loss in…
- « Previous Page
- 1
- …
- 12
- 13
- 14
- 15
- 16
- …
- 33
- Next Page »