MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Positron emission tomography(PET)"

  • 2019 International Congress

    Visual hallucinations in Parkinson´s disease and amyloid burden: 18F-Flutemetamol PET-MRI study

    B. Fernández-Rodríguez, C. Gasca-Salas, R. Rodríguez-Rojas, P. Guida, D. Mata-Marín, I. Obeso-Martín, L. Vela, M. Garcerant-Tafur, L. García-Cañamaque, JA. Obeso (Móstoles, Spain)

    Objective: To compare amyloid distribution in patients with Parkinson´s disease (PD) with visual hallucinations (VH-p) and without (VH-n). Background: In patients with PD the prevalence…
  • 2019 International Congress

    Is 18F-FDG-PET/CT a helpful tool to diagnose PSP clinical variants?

    G. Marti-Andres, M. Riverol-Fernandez, R. Valentí-Azcárate, M. Fernández-Matarrubia, E. Prieto-Azcárate, J. Arbizu-Azcarate, MR. Luquin-Piudo (Pamplona, Spain)

    Objective: To assess if there are differential metabolic brain patterns among Progressive Supranuclear Palsy(PSP) clinical variants and between them and Parkinson’s disease patients (PD). Background:…
  • 2019 International Congress

    Evaluation of Imidazoline 2 binding sites reflecting astroglia pathology in Huntington’s Disease: An in vivo [11C]BU99008 PET study

    H. Wilson, F. Niccolini, G. Dervenoulas, R. Tyacke, J. Myers, R. Gunn, D. Nutt, E. Rabiner, S. Tabrizi, M. Politis (London, United Kingdom)

    Objective: We aimed to evaluate the role of astroglia activation in Huntington’s disease gene expansion carriers (HDGECs) using [11C]BU99008 PET, a novel radioligand with high specificity and…
  • 2019 International Congress

    Functional connectivity and microstructural alterations in regions of synaptic density loss in DLB and PDD

    T. Yousaf, G. Dervenoulas, G. Pagano, C. Loane, H. Wilson, A. Chandra, O. Cousins, R. Gunn, E. Rabiner, F. Niccolini, M. Esposito, L. Ricciardi, D. Aarsland, M. Politis (London, United Kingdom)

    Objective: We aimed to investigate whether functional connectivity and white matter integrity is altered in regions exhibiting reduced synaptic density, as measured by [11C]UCB-J-PET,in Dementia with…
  • 2019 International Congress

    11C-PBB3 PET in PD: does alpha-synuclein pathology start in axonal terminals?

    M. Matarazzo, A. Pérez-Soriano, V. Sossi, N. Vafai, E. Shahinfard, K. Ju-Chieh Cheng, J. Mckenzie, N. Neilson, Q. Miao, H. Shinotoh, M. Higuchi, A. Stoessl (Vancouver, BC, Canada)

    Objective: To use 11C-PBB3 PET binding to monitor alpha-synuclein (a-syn) pathology in PD subjects in vivo. Background: In previous work we have shown binding of…
  • 2019 International Congress

    The role of Synaptic vesicle protein 2A (SV2A) in patients with Parkinson’s disease dementia and Dementia with Lewy bodies: An in vivo [11C]UCB-J PET study

    H. Wilson, G. Dervenoulas, G. Pagano, A. Chandra, F. Niccolini, M. Esposito, R. Gunn, L. Ricciardi, E. Rabiner, D. Aarsland, M. Politis (London, United Kingdom)

    Objective: We aimed to investigate the role of synaptic vesicle glycoprotein 2A (SV2A) in Parkinson’s disease dementia (PDD) and Dementia with Lewy bodies (DLB) using…
  • 2019 International Congress

    Multimodal PET and fcMRI reveals regional modulation by STN DBS correlating to motor outcomes

    J. Younce, A. Tanenbaum, M. Campbell, J. Perlmutter, S. Norris (St Louis, MO, USA)

    Objective: To define brain networks modulated by deep brain stimulation (DBS) of the subthalamic nucleus (STN) and correlate connectivity with motor outcomes. Background: STN DBS…
  • 2019 International Congress

    Relationship between symptoms and regional density of metabotropic glutamate receptors subtype 1 measured with 11C-ITMM PET in de novo Parkinson’s disease

    K. Ishiwata, K. Kimura, MR. Zhang, J. Toyohara, K. Wagatsuma, M. Sakata, K. Ishibashi, K. Ishii, M. Suzuki, M. Mishina (Kawasaki, Japan)

    Objective: To investigate correlations of motor and non-motor symptoms with the brain densitiesof the metabotropic glutamate receptor subtype 1 (mGluR1) in de novo Parkinson’s disease…
  • 2019 International Congress

    Comparison between [11C]PE2I PET and [123I]FP-CIT SPECT as markers of DAT expression in early Parkinson’s disease

    T. Yousaf, G. Pagano, H. Wilson, B. Corcoran, G. Vivian, M. Politis (London, United Kingdom)

    Objective: To compare single-photon emission computed tomography (SPECT) with [123I]FP-CIT and positron emission tomography (PET) with [11C]PE2I as markers of dopamine transporter (DAT) loss in…
  • 2019 International Congress

    FDG PET: a good predictive tool for CNS inflammation

    M. Nader, F. Fluchere, T. Witjas, A. Eusebio, JP. Azulay (Marseille, France)

    Objective: 1)When to suspect an underlying autoimmune process in patients presenting with parkinsonism. 2)To highlight the importance of FDG PET as a complementary exam in…
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