In vivo relationship between synaptic density and functional connectivity in progressive supranuclear palsy: a multimodal [11C]UCB-J PET and resting state fMRI study.
Objective: To assess the relationship between synaptic density and functional connectivity in the primary tauopathy of Progressive Supranuclear Palsy (PSP). Background: PSP is a debilitating…Plasma microRNA expression profiling in patients with progressive supranuclear palsy. A five-microRNA panel in plasma was identified as a potential biomarker for progressive supranuclear palsy
Objective: Our objective was to identify differentially expressed, circulating miRNAs in PSP which could serve as diagnostic biomarker for this disease. Background: Progressive supranuclear palsy…Clinical variants of PSP: phenotypical convergence and its relationship with the brain glucose metabolism
Objective: To evaluate the phenotypical convergence phenomena among a cohort of different PSP variants. We also aimed to evaluate the possible correlations of the regional…Rare Neurodegenerative Phenotypes in Patients Carrying Homozygous GBA1 Mutations
Objective: To describe patients with Type 1 Gaucher disease who developed a rare neurodegenerative disease other than synucleinopathies. Background: Lysosomal dysfunction as a contributor to…Visualising tau in patients with progressive supranuclear palsy using PI2620-PET
Objective: This study investigates the use of a new tau-specific PET radiotracer, [18F]-PI-2620, as a tool for visualising tau in the living brain. Background: The…Reduced cerebral energy metabolism in Parkinson’s disease in contrast to Progressive Supranuclear Palsy
Objective: To determine the significance of 31P-MRSI to differentiate between idiopathic Parkinson’s disease (PD), Progressive supranuclear palsy (PSP), and healthy control subjects. Background: Bioenergetic disturbances,…Fatigue in patients with progressive supranuclear palsy
Objective: To investigate prevalence and clinical impact of fatigue in the patients with progressive supranuclear palsy Background: Fatigue is a common and disabling non-motor symptom…Cerebrospinal fluid levels of oxidative stress measured using diacron-reactive oxygen metabolites and biological antioxidant potential in patients with Parkinson’s disease and progressive supranuclear palsy
Objective: We aimed to evaluate cerebrospinal fluid (CSF) levels of oxidative stress (OS) and antioxidant potential using diacron-reactive oxygen metabolites (d-ROMs) and biological antioxidant potential…Novel Cognitive Markers for Early Diagnosis and Monitoring of Progressive Supranuclear Palsy
Objective: The aim of this study was to evaluate whether a novel computerised test could offer an inexpensive and reliable tool that can aid diagnosis…The Use Of Bioness L300 Go Results In Functional Gait Improvement In Patients With Parkinson’s Plus Syndromes.
Objective: To describe the efficacy of use of Bioness L300 Go FES System to result in functional improvement in gait related impairments in persons with…
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