Effect of simultaneous mGlu2 positive allosteric modulation and orthosteric stimulation combined with 5-HT2A antagonism on psychosis-like behaviours, dyskinesia and parkinsonism in the MPTP-lesioned marmoset
Objective: To assess the effects of concurrent metabotropic glutamate type 2 (mGlu2) positive allosteric modulation and orthosteric stimulation combined with serotonin type 2A (5-HT2A) antagonism.…Neuropsychiatric Issues in Parkinson’s Disease
Objective: The aim of this study is to analyze the epidemiology, clinical features and treatment approaches for NPS in PD. Background: Parkinson's disease (PD) is…Evaluation of bedside tests of attention in delirium superimposed on Parkinson’s disease and dementia
Objective: To evaluate the ability of simple bedside tests for attention to detect delirium in those with and without underlying neurodegenerative diseases, including Parkinson’s disease…Fatal Psychosis in a young Girl
Objective: We describe a 24-year young female who presented to us with features of Neurolept malignant syndrome. She was later evaluated and found to have…Effect of the GlyT1 inhibitor ALX-5407 on dyskinesia, psychosis-like behaviours and parkinsonism in the MPTP-lesioned marmoset
Objective: To determine the effect of glycine transporter 1 (GlyT1) inhibition with ALX-5407 on dyskinesia, psychosis-like behaviours (PLBs) and parkinsonism severity in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-lesioned…Prospective investigation of the frequency of tardive syndromes in outpatients attending two specialist psychiatry hospitals in Lagos, Nigeria
Objective: To determine the frequency and profile of TS in persons on antipsychotics attending tertiary psychiatry hospitals. Background: The term tardive syndrome (TS) encompasses the…Incidence and survival of psychosis in patients with Parkinson’s Disease (1991-2010)
Objective: To determine the incidence of psychosis in patients with Parkinson's disease (PD) and to investigate the survival after a psychosis diagnosis among an incident…Improving Hospital Outcomes through the Aware in Care Ambassador Program
Objective: The objective is to analyze the impact of the Aware in Care (AIC) Ambassador program in accomplishing its three goals regarding hospitalization of people…The Future of Hospitalization for People with Parkinson’s Disease
Objective: To share the discussion of the December 6, 2019 Parkinson’s Hospitalization Convening. Background: On December 6, 2019, The Parkinson’s Foundation (PF) assembled thought leaders…Behavioral and Psychological Symptoms in Patients with Movement Disorders
Objective: To find out the prevalence of neuropsychiatric symptoms in patients with Movement Disorders. To find out the relationship between cognitive impairment and neuropsychiatric symptoms…
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