Fatal Psychosis in a young Girl
Objective: We describe a 24-year young female who presented to us with features of Neurolept malignant syndrome. She was later evaluated and found to have…Effect of the GlyT1 inhibitor ALX-5407 on dyskinesia, psychosis-like behaviours and parkinsonism in the MPTP-lesioned marmoset
Objective: To determine the effect of glycine transporter 1 (GlyT1) inhibition with ALX-5407 on dyskinesia, psychosis-like behaviours (PLBs) and parkinsonism severity in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-lesioned…Effect of simultaneous mGlu2 positive allosteric modulation and orthosteric stimulation combined with 5-HT2A antagonism on psychosis-like behaviours, dyskinesia and parkinsonism in the MPTP-lesioned marmoset
Objective: To assess the effects of concurrent metabotropic glutamate type 2 (mGlu2) positive allosteric modulation and orthosteric stimulation combined with serotonin type 2A (5-HT2A) antagonism.…Neuropsychiatric Issues in Parkinson’s Disease
Objective: The aim of this study is to analyze the epidemiology, clinical features and treatment approaches for NPS in PD. Background: Parkinson's disease (PD) is…Evaluation of bedside tests of attention in delirium superimposed on Parkinson’s disease and dementia
Objective: To evaluate the ability of simple bedside tests for attention to detect delirium in those with and without underlying neurodegenerative diseases, including Parkinson’s disease…Increased risk of Parkinson’s disease in patients with schizophrenia spectrum disorders
Objective: To investigate the coincidence of Parkinson’s disease (PD) and schizophrenia spectrum disorders (SCD). Background: PD is characterized by a progressive loss of mesostriatal dopamine…Homer1 polymorphism in patients with Parkinson’s disease and psychosis
Objective: To explore the association of psychosis in Parkinson’s disease with polymorphisms of HOMER1, a gene whose product (Homer1) is responsible for modulating the metabotropic…Attitudes of Care Partners Toward Medications for Parkinson’s Disease Psychosis
Objective: To explore attitudes regarding use of medications among care partners of individuals with Parkinson’s disease psychosis. Background: Parkinson’s disease (PD) psychosis is a highly…Mental Health Matters Too – Integration of physical and mental health in a multidisciplinary Parkinson’s Clinic
Objective: The overall aim of the project was to demonstrate that people with Parkinson’s disease benefit from good mental health care when mental health services…All-cause mortality in pimavanserin and atypical antipsychotic users with Parkinson’s disease in Medicare
Objective: To assess all-cause mortality in Medicare beneficiaries with Parkinson’s disease (PD) receiving pimavanserin or atypical antipsychotics (AAs). Background: In PD patients, the lifetime prevalence…
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