Are patients presenting earlier in time? Secular changes in REM sleep behavior disorder
Objective: To determine if secular changes occur in REM sleep behavior disorder (RBD). Background: RBD is the strongest clinical marker of prodromal synucleinopathy, and provides…Sympathetic tone abnormalities in subjects at risk for Parkinson’s Disease without evidence of nigrostriatal neurodegeneration: a multimodal biomarker study
Objective: To study autonomic dysfunction in subjects with idiopathic REM sleep behavior disorder (iRBD) and at least one pre-motor symptom of Parkinson's disease (PD). Background:…Sleep disorders and their relationship to non-motor symptoms in Mexican Parkinson’s disease patients
Objective: Analyze the impact of sleep disorders (SD) on the severity of non-motor symptoms (NMS) in Parkinson’s Disease (PD) patients Background: Sleep is a physiological…Longitudinal changes in brain networks associated with clinical symptoms in idiopathic rapid eye movement sleep behavior disorder
Objective: We aimed to assess changes in brain functional networks and accompanying symptoms over years in patients with idiopathic rapid eye movement sleep behavior disorder…Prevalence and severity of non-motor symptoms in hispanic at-risk population with REM-sleep behavior disorder.
Objective: To detect non-motor symptoms in individuals at-risk for Parkinson's disease (PD) due to idiopathic REM sleep behavior disorder (RBD) and determine the rate of…Cortical thickness and global atrophy progression in Parkinson’s disease with probable RBD
Objective: To explore 3-year cortical thickness (CTh) and global atrophy progression in treated Parkinson’s disease (PD) with probable REM sleep behavior disorder (RBD). Background: Parkinson’s…Cortical mean diffusivity changes in Parkinson’s disease with probable RBD
Objective: To investigate cortical mean diffusivity (cMD) as a sensitive measure to identify subtle microstructural cortical changes in Parkinson’s disease (PD) patients with probable REM…Sleep stability, arousals and cycle structure in alfa-synucleinopathies: a comparative study between isolated REM sleep behaviour disorder (iRBD), Parkinson’s Disease (PD) and Dementia with Lewy Bodies (DLB)
Objective: To compare sleep stability, arousals and sleep cycle structure between two sets of diagnosis: iRBD vs PD vs DLB; patients with RBD (RBD+) vs…Feasibility of artificial intelligence in predicting early phenotype conversion of REM Sleep Behavior Disorder
Objective: The goal of this study was to investigate the feasibility of deep learning in the prediction of disease conversion in RBD patients. Background: Rapid…Design of a prodromal screening study for subtypes in Parkinson’s Disease
Objective: To follow-up prodromal Parkinson’s Disease (PD) subtypes in a longitudinal cohort study, validating new biomarkers and ethical guidelines for early detection of PD. Background:…
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