Anti-α-synuclein antibody 5G4 differentiates idiopathic REM Sleep Behavior Disorder patients from healthy controls in skin biopsies
Objective: The aim of our study was to assess α-synuclein (α-syn) staining using the 5G4 antibody in skin samples of patients with idiopathic REM Sleep…Central olfactory structure atrophy is linked to synucleinopathy conversion in idiopathic REM sleep behavior disorder
Objective: We hypothesized that early structural changes in the brain olfactory relevant structures may help early identification of those at risk of future disease conversion…Automated scoring of REM sleep without atonia using the open-source software RBDtector
Objective: To facilitate quantification of REM sleep without atonia (RSWA) and thereby identify patients with rapid eye movement (REM) sleep behaviour disorder (RBD). Background: RBD…Distribution of rapid eye movement (REM) sleep without atonia (RWA) across the REM cycles.
Objective: This study aimed to evaluate whether rapid eye movement )REM( sleep without atonia )RWA( is similar throughout multiple REM cycles during one night. Background:…Affected tongue movements in idiopathic REM sleep behavior disorder
Objective: In Parkinson’s disease (PD), recognition of speech deviations often follows clinical diagnosis. But what if speech is a prodromal biomarker in PD? The study…Sleep stability, arousals and cycle structure in alfa-synucleinopathies: a comparative study between isolated REM sleep behaviour disorder (iRBD), Parkinson’s Disease (PD) and Dementia with Lewy Bodies (DLB)
Objective: To compare sleep stability, arousals and sleep cycle structure between two sets of diagnosis: iRBD vs PD vs DLB; patients with RBD (RBD+) vs…Feasibility of artificial intelligence in predicting early phenotype conversion of REM Sleep Behavior Disorder
Objective: The goal of this study was to investigate the feasibility of deep learning in the prediction of disease conversion in RBD patients. Background: Rapid…Design of a prodromal screening study for subtypes in Parkinson’s Disease
Objective: To follow-up prodromal Parkinson’s Disease (PD) subtypes in a longitudinal cohort study, validating new biomarkers and ethical guidelines for early detection of PD. Background:…Relationship between brain bioelectrical activity during REM/NREM sleep, grey matter changes and visual disorders in patients with RBD in Parkinson’s disease
Objective: To investigate the brain bioelectric activity during REM/NREM sleep and determine the relationship with visual impairment and structural brain alteration in non-demented PD patients…The Functional Impact of REM Sleep Behavior Disorder in Parkinson’s Disease with Mild Cognitive Impairment
Objective: This study examines whether severity and the functional impact of cognitive decline in Parkinson’s disease mild cognitive impairment (PD MCI) participants differ between those…
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