Risk factors in a population with high prevalence of Parkinson’s disease in Chile
Objective: The aim of this study was to investigate the frequency of environmental risk factors, comorbidities and family history in a population with Pakinson disease…Brain Energetics: Changes in Healthy Aging and Parkinson’s Disease
Objective: To identify in vivo bioenergetic alterations in healthy aging and Parkinson’s disease (PD). Background: PD-related cerebral metabolic alterations have been robustly characterized [1] and…Metabolic Imaging Correlates of Apathy in Parkinson’s Disease.
Objective: To investigate apathy-associated metabolic changes in Parkinson’s disease. Background: Apathy is a behavioral syndrome manifested as a decrease in goal-directed behaviors. It has been…Striatal dopamine- and basal forebrain cholinergic-dependent brain metabolism and cognition in Parkinson’s disease
Objective: To explore the interrelation of striatal dopamine, cholinergic basal forebrain volume, brain metabolism, and cognition in PD. Background: Parkinson’s disease (PD) involves multiple neurotransmitter…Seed-based Metabolic Networks and Time Series Variation based on Functional [18F]-FDG PET in Parkinson’s Disease
Objective: To analyse seed-based metabolic networks and time series variation in Parkinson’s disease with and without mild cognitive impairment based on functional PET (fPET) Background:…Longitudinal Relationship Between Brain Metabolism and Clinical Changes in Huntington’s Disease
Objective: To understand the relationship between progression of the clinical symptoms and patterns of brain hypometabolism progression in a large cohort of Huntington’s disease (HD)…Effects of striatal dopamine depletion and altered brain metabolism on Parkinson’s disease
Objective: To investigate the relationship between striatal dopamine depletion, altered brain metabolism, motor deficits, and cognitive dysfunction in Parkinson’s disease (PD) Background: PD shows degeneration…The alteration of GABA and glutamate in Parkinson’s disease is related to motor executive dysfunction: a 7T-MRS study
Objective: To explore the possible metabolic alterations of primary motor cortices (M1) of Parkinson’s disease (PD) patients and prodromal PD using 7T proton magnetic resonance…Metabolic connectivity assessed by dynamic FDG-fPET acquisition in Parkinson’s disease: a multimodal fPET and fMRI study
Objective: To examine the spatial convergence of hemodynamic and metabolic network characteristics based on dynamic [18F]FDG-fPET acquisition Background: While fMRI reveals within-subject hemodynamics, [18F]FDG-PET traditionally…Patterns of Parkinson disease mitochondrial brain function indexed by 31P magnetic resonance spectroscopy
Objective: To examine whether individuals with PD show greater temporal than frontal high energy phosphate metabolism (31P MRS ATP) that is similar or different from…
