Analyzing the metabolic function of DJ-1 in the pathogenesis of Parkinson`s disease (PD) and Glioblastoma multiforme (GBM)
Objective: In this project, we are comprehensively studying the function of DJ-1 in PD and GBM to better understand its observed role in both, neurodegeneration…BRAIN REGIONAL HYPOMETABOLISM PROGRESSION IN iRBD: THE COGNITIVE ROLE OF OCCIPITAL HYPOMETABOLISM
Objective: To understand functional brain changes over time in isolated REM sleep behaviour disorder (iRBD), we investigated the progression of regional hypometabolism in iRBD patients…Reconfiguration of Functional Motor Connectome after MRgFUS Vim Thalamotomy in Essential Tremors
Objective: Our primary endpoint was to verify whether rs-FC between tremor-related areas was effectively modulated by MRgFUS at 1 and 3 months post-operatively. Alongside, we…Progression of Syndrome Specific Metabolic Brain Patterns in Patients with Various Parkinsonian Syndromes
Objective: To analyse the follow-up changes in the expression of the three syndrome specific metabolic patterns in a cohort of parkinsonian patients who underwent 18F-FDG…Insulin resistance and Parkinson’s disease
Objective: To investigate peripheral insulin resistance and cerebral FDG-PET changes in Parkinson’s disease (PD). Background: Glycated hemoglobin levels (HbA1c) is used as a marker of…Metabolic patterns and neurodegeneration in isolated REM sleep behavior disorder
Objective: To elucidate the role of Parkinson’s disease (PD)-related brain metabolic patterns as a biomarker in isolated rapid-eye-movement sleep behavior disorder (iRBD) for clinical correlation…Abnormal Cerebral Glucose Metabolism and Dopaminergic Dysfunction in Patients with Parkinson’s Disease with Bilateral Onset
Objective: To explore the characteristics of the abnormal cerebral glucose metabolism and dopamine distribution in patients with Parkinson's disease (PD) with bilateral onset. Background: PD is…Altered metabolic and functional resting state activity in cognitively unimpaired and impaired Parkinson’s disease patients
Objective: To assess the correspondence between functional connectivity and metabolic covariance in healthy controls and Parkinson’s disease patients (PD) with and without cognitive impairment. Background:…Central Insulin Resistance Index is Independent of Peripheral Insulin Resistance in Parkinson’s disease
Objective: To correlate brain insulin signalling with peripheral insulin resistance using neuronally derived blood exosomes in patients with Parkinson's Disease (PD) Background: Insulin signaling abnormalities may…Imaging Brain Insulin Resistance in Parkinson’s Disease using [¹⁸F]FDG-PET
Objective: To obtain a glucose brain uptake survey of Parkinson's Disease (PD) patients with or without insulin resistance (IR). Background: IR is common in PD…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.