Time-to-event approach mitigates the treatment masking effect of symptomatics on MDS-UPDRS Part III
Objective: To assess whether a time-to-event (TTE) approach may mitigate the masking effect of changing symptomatic therapy on Movement Disorders Society–Unified Parkinson’s Disease (PD) Rating…Evaluation of ocular perfusion in Parkinson’s disease and association with clinical manifestations.
Objective: To evaluate optic nerve head and macular perfusion in subjects with Parkinson's disease (PD) and its association with clinical manifestations. Background: PD is associated…The reliability and validity of the Ziegler test for measuring freezing of gait in people with Parkinson’s disease.
Objective: To determine the inter-rater and test-retest reliability of the Ziegler test to measure freezing of gait (FOG) severity in people with Parkinson’s disease (PwPD).…Screening of REM Sleep Behavior Disorder and the relation with parkinsonism symptoms in the elderly in southern Brazil: a preliminary population-based study
Objective: To describe the preliminary screening profile for suspected REM sleep behavior disorders (RBD) and association with parkinsonian symptoms in the elderly in a population-based…Development and validation of clinical scales for defining RBD severity in participants of the North American Prodromal Synucleinopathy (NAPS) consortium
Objective: The objective of this study is to assess the internal validity of the REM Sleep Behavior Disorder (RBD) symptom severity scale (RBDSSS) and its…Long-term Deutetrabenazine Safety on Motor, Psychiatric, and Cognitive Measures in Individuals With Chorea Associated With Huntington Disease
Objective: To evaluate long-term deutetrabenazine safety on motor, psychiatric, and cognitive measures in participants with chorea associated with Huntington disease (HD). Background: Deutetrabenazine, a vesicular…Developmental Validity of the revised improved version of the Fragile X-associated Tremor Ataxia Syndrome Rating Scale (FXTAS-RS)
Objective: To qualitatively validate the revised improved version of the Fragile X-associated Tremor Ataxia Syndrome Rating Scale (FXTAS-RS) for motor signs assessment. Background: Clinimetric analyses…Impact of the delayed diagnosis in the prognosis of Parkinson’s disease.
Objective: To evaluate the difference of motor and non-motor dysfunction, and quality of life in Parkinson’s disease (PD) patients with and without delayed diagnosis. Background:…The Comparison of Constipation scoring system scales between Parkinson’s disease and non-Parkinson’s disease patients with constipation
Objective: This study aims to identify differences of constipation symptoms in detail by using the constipation scoring system between PD patients and non-PD patients. Background:…Exploratory delayed-start analysis of PASADENA evaluating the efficacy of prasinezumab on motor progression and motor complications in early-stage Parkinson’s disease
Objective: To evaluate the effect of prasinezumab on motor progression and motor complications in early-stage Parkinson’s disease (PD) using an exploratory delayed-start analysis of Part…
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