Validation of a patient-reported functional mobility composite score (FMCS) in people with typical Parkinson’s disease
Objective: To investigate the convergent and discriminative validity of a patient-reported FMCS in people with typical PD (PwP). Background: Although a patient-reported instrument is less…Estimating the Meaningful Within-Patient Change Threshold for the MDS-UPDRS Part III
Objective: To estimate the meaningful within-patient worsening threshold (MWPWT) of the Movement Disorders Society–Unified Parkinson’s Disease Rating Scale (MDS-UPDRS Part III in early-stage Parkinson's disease…Cerebellar and other motor symptoms in Huntington’s Disease: A multiple scale correlation study
Objective: To describe the cerebellar symptoms and other accompanying movement disorders in Huntington's Disease (HD). Background: HD is a pathological entity whose etiological substrate is…Translation and validation of two Parkinson’s disease specific burden questionnaires from German into French.
Objective: The study purpose was to translate the questionnaires and to evaluate their internal consistency and temporal stability in a French study population, composed of…Validation of biomarkers in Huntington’s disease to support the development of disease-modifying therapies: a systematic review and critical appraisal scheme
Objective: To review studies for disease progression biomarkers published in HD and evaluate their methodological quality in a standardized manner. Background: Huntington disease (HD) is a fatal autosomal dominant neurodegenerative condition that starts to manifest clinically around the 4th decade of life. There are promising novel genetic-based therapies under development intended to modify the disease trajectory. Valid…The impact of gender identity and gender role orientation on health-related quality of life in people with Parkinson’s disease.
Objective: To assess the associations of gender identity and gender role orientation with health-related quality of life (HRQoL) among persons with Parkinson’s disease (PD). Background:…Relationship of satisfaction and adherence in remote digital monitoring: Results from a clinical drug trial in early Parkinson’s disease
Objective: To investigate satisfaction with daily remote monitoring with a digital health technology tool (DHTT) in individuals with early Parkinson’s disease (PD) and the relationship…Emergence of new symptoms in experiences of daily living in early Parkinson’s disease
Objective: To explore the utility of assessing emergence of new symptoms (ES) impacting the daily experiences of patients with early Parkinson’s disease (PD) in relation…The Role of the PD Diary Trainer/Reviewer in Parkinson’s Disease Clinical Trials
Objective: To examine the experience profile of PD Diary raters in clinical trials Background: The Parkinson’s Disease (PD) Home Diary (Hauser, 2000)1 is a widely…Does MDS-UPDRS provide greater sensitivity to mild disease than UPDRS for assessing motor severity in early Parkinson’s disease?
Objective: To test whether The Movement Disorder Society revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Part III (Motor Examination) items provide increased sensitivity…
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