Effect of polygenic load on striatal dopaminergic deterioration in Parkinson’s disease
Objective: To investigate the longitudinal association between PD-associated polygenic load and the striatal dopaminergic activity using 123I-N-3-fluoropropyl-2-beta-carboxymethoxy-3beta-(4-iodophenyl) nortropane (123I-FP-CIT) single photon emission computed tomography (SPECT).…Age-related failure in compensatory mechanisms and its relation to the Parkinson phenotype: evidence from a SPECT study in early and late-onset PD
Objective: To investigate if a less prominent dopaminergic dysfunction on 123I-ioflupane SPECT imaging (DaTSCAN) despite a more severe motor phenotype in Late Onset Parkinson’s Disease…Atypical Dopamine Responsive Parkinsonism in HIV Seroconversion
Objective: To add to the current body of knowledge of the association of HIV infection and dopamine responsive parkinsonism. Background: South Africa has one of…Striatal FP-CIT SPECT findings for progressive supranuclear palsy subtypes
Objective: In our previous study FP-CIT SPECT (FP-CIT) in progressive supranuclear palsy-Parkinsonism (PSP-P) revealed higher anterior striatal accumulation, and PSP- Richardson’s syndrome (PSP-RS) revealed lower…Opposite effects of dopamine on specific NoGo perfomance in young and late onset Parkinson’s disease and the relationship to nigrostriatal degeneration
Objective: To investigate inhibitory control under dopamine (DA) in Parkinson’s disease (PD). Background: The pattern of degeneration in PD as well as side effects of…A unique case of DAT positive Parkinson’s disease along with a mutable Huntington’s gene
Objective: The aim of this abstract is to report a unique case of DAT positive Parkinson’s disease with a mutable Huntington’s gene. Background: Huntington’s disease…Genetic variations of SNCA and striatal dopaminergic dysfunction in patients with Parkinson’s disease
Objective: The aim of the present study was to investigate genetic variants in SNCA associated with accelerated deterioration in striatal dopaminergic activity. Background: Widespread a-synuclein…DAT-imaging and clinical phenotypes of Parkinson’s disease
Objective: To evaluate the relationship of motor and nonmotor symptoms with striatal dopaminergic denervation in a cohort of symptomatic PD patients with positive DAT-imaging Background:…Bupropion causing misdiagnosis in brain dopamine transporter imaging for parkinsonism
Objective: To report long-lasting effects of bupropion on brain dopamine transporter (DAT) binding in a patient with depression and parkinsonism. Background: Striatal DAT imaging is…Can Preoperative Dopamine Transporter Imaging Predict the Long-Term Outcome of Deep Brain Stimulation in Patients with Parkinson’s Disease?
Objective: The aim of this study is to examine how baseline dopamine transporter imaging, DAT SPECT, is related to the long-term outcome of STN DBS…
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