Optimization of deep brain stimulation in STN among patients with Parkinson’s disease using a novel EEG-based tool
Objective: The current study aims to develop an innovative method for objective differentiation between the locations of the four DBS contacts in the various parts…Long Term Outcome of the Subthalamic Nucleus DBS for Advanced Parkinson’s Disease: An Eight Years Follow-Up Study in China
Objective: To investigate the long term efficacy and its safety of STN DBS for PD in China with an eight years follow up of ten…Cerebrospinal fluid protein biomarkers in PD patients after DBS-STN surgery: A retrospective analysis of patients that underwent surgery between 1993 and 2001
Objective: To investigate cerebrospinal fluid (CSF) markers of neurodegeneration [neurofilament light chain (NFL), total Tau (T-Tau)], tau pathology [phosphorylated tau (p-Tau)], glial cell damage or…Beneficial nonmotor effects of subthalamic and pallidal DBS in Parkinson’s disease
Objective: To investigate nonmotor effects of bilateral subthalamic (STN) and pallidal (GPi) deep brain stimulation (DBS) in Parkinson’s disease (PD). Background: Bilateral STN-DBS as well…Tractographically defined subthalamic connectivity is associated with apathy in Parkinson’s disease and healthy subjects
Objective: We aimed to study the baseline white matter characteristics of tractographically defined subthalamic connectivity using Diffusion Tensor Imaging in Parkinson's Disease patients and healthy…INTREPID: A Prospective, Double Blinded, Multicenter Randomized Controlled Trial Evaluating Deep Brain Stimulation with a New Multiple Source, Constant Current Rechargeable System in Parkinson’s disease
Objective: INTREPID is designed to assess the improvement in motor function and quality of life in patients with Parkinson’s disease (PD) following Deep Brain Stimulation…Comparison of low-frequency stimulation versus high-frequency stimulation of the subthalamic nucleus on cerebral hemodynamics in Parkinson’s disease: A transcranial Doppler Study
Objective: Parkinson’s disease (PD) is the second most frequent progressive neuro-degenerative disease and the Deep Brain Stimulation (DBS) is a useful surgical treatment to treat…Patterns of rhythmic single unit activity of the subthalamic nucleus in patients with Parkinson’s disease
Objective: The study of rhythmic neuronal activity is of great interest as they may have implications for pathophysiological mechanisms of PD. The aim of this…Intraoperative local field potential recordings from deep brain stimulation electrodes help predict efficacy of subthalamic nucleus stimulation in patients with Parkinson’s disease
Objective: Subthalamic nucleus (STN) deep brain stimulation(DBS) is an effective treatment for advanced Parkinson's disease (PD). Two electrophysiological techniques aid identification of the optimal target.…Surgery-, hardware – and chronic stimulation-related adverse events following subthalamic nucleus deep brain stimulation for Parkinson’s disease
Objective: To evaluate the adverse events (AEs) following subthalamic nucleus (STN) deep brain stimulation (DBS) for Parkinson’s disease (PD) during 6 years period. Background: The…
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