Investigating Impaired Perceptual Decision Making in Cervical Dystonia: A novel paradigm integrating Behavioural and Neural measures
Objective: This research aimed to develop a paradigm measuring perceptual decision making (PDM) to test the hypothesis of impaired PDM in cervical dystonia patients. Background:…Visual dysfunction of the Superior Colliculus in idiopathic Blepharospasm: a pilot study
Objective: To investigate the role of the superior colliculus (SC) using functional brain MRI (fMRI) and a visual stimulation paradigm based on luminance contrast variations…Transcranial neuromodulation of the Frontal Eye Fields: targeting Temporal Discrimination Thresholds (TDT) in Adult Onset Primary Torsion Dystonia (AOPTD)
Objective: We aim to further characterise the sensory processing abnormalities previously observed in AOPTD using a novel transcranial Direct Current Stimulation (tDCS) protocol. Background: AOPTD,…Optimization of Region of Interest Analysis of the Superior Colliculus for Improved Activation Detection in Cervical Dystonia
Objective: Optimization of Region of Interest (ROI) Analysis of the Superior Colliculus for Improved Activation Detection in Cervical Dystonia Background: Cervical dystonia (CD) is a…Head turning onset and velocity in response to a peripheral visual stimulus in cervical dystonia patients, their unaffected relatives with and without abnormal temporal discrimination and healthy controls.
Objective: We postulate that cephalomotor responses (onset of head turning and speed of head turning) to the appearance of a novel peripheral visual stimulus will…Disrupted superior collicular activity may reveal cervical dystonia disease pathomechanisms
Objective: To assess by functional magnetic resonance imaging, the response of the superior colliculi to a looming stimulus in cervical dystonia patients and their unaffected…The Superior Colliculus is impaired in de novo Parkinson’s disease patients
Objective: To study the function of the Superior Colliculus (SC) in de novo Parkinson’s disease (PD) patients. Background: The SC function is impaired in parkinsonian…Impaired temporal coupling of action and perception in Parkinson’s disease
Objective: To study in Parkinson's disease (PD) the dependence of saccadic and perceptual reaction times (SRT and PRT) upon the temporal asynchrony (TA) between central…A functional magnetic imaging study of the response in the superior colliculus to looming stimuli in cervical dystonia patients and their relatives
Objective: To demonstrate the functional magnetic resonance imaging response to looming stimuli in the superior colliculus of cervical dystonia patients and their relatives with and…A dynamic causal model of the superior colliculus: Inhibitory activity increases with the temporal discrimination threshold
Objective: To investigate if abnormalities observed in the putamen of unaffected first-degree relatives (of cervical dystonia patients) with abnormal temporal discrimination thresholds (TDT) are a…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.