Three patients with PSP presenting with a logopenic pattern of aphasia: expanding the phenotype of language impairment in PSP.
Objective: To investigate the a series of cases presenting with apparent logopenic variant primary progressive aphasia who then developed symptoms suggestive of PSP. Background: Deficits…Neuropathological profile of tauopathy in spinocerebellar ataxia type 8
Objective: The purpose of this study is to examine the distribution of tau pathology in brain regions of patients with spinocerebellar ataxia type 8 (SCA8).…Probable Four-repeat tauopathy criteria in Corticobasal Syndrome: diagnostic accuracy, clinical features and imaging biomarkers
Objective: To compare the “probable four-repeat (4R)-tauopathy” criteria[1] with the clinical research(cr) criteria for corticobasal degeneration (CBD) [2] regarding diagnostic accuracy to predict a negative…Variability in Age of Onset, Age of Diagnosis and Age of Death for Progressive Supranuclear Palsy Patients Among Three Racial Groups in Hawai`i
Objective: To examine if differences in age of symptom onset, age of diagnosis, age of death, and number of years lived after diagnosis exist for…No association between naturally occurring plasma tau autoantibodies and movement disorders
Objective: To determine if there is an association between the presence of naturally occurring plasma tau autoantibodies and a movement disorder diagnosis. Background: The microtubule-associated…CSF biomarkers in neurodegenerative parkinsonism can distinguish between multiple system atrophy and 4-repeat tauopathies, but not between disease with Lewy bodies and multiple system atrophy
Objective: To assess the usefulness of a defined set of blood-based and cerebrospinal fluid-based biomarkers in the differential diagnosis of neurodegenerative proteinopathies. Background: The diagnostic…Complications in Patients with Progressive Supranuclear Palsy
Objective: This study elucidated the incidence and features of complications in patients with progressive supranuclear palsy (PSP). Background: PSP is a progressive neurodegenerative disorder accompanied…Pan India Registry for Progressive Supranuclear Palsy (PAIR-PSP)
Objective: To understand Progressive Supranuclear palsy (PSP) phenotype and genotype from India. Background: Insights into PSP pathophysiology and newer clinical phenotypes are increasingly being recognized.…Plasma p-tau181 is increased in Lewy body dementia and relates to cognitive performance
Objective: To compare plasma p-tau181 concentration in Parkinson’s disease (PD), Lewy body dementia (LBD) and healthy controls and to examine the relationship between ptau-181 concentration…In-vivo measurement of tau depositions in anti-IgLON5 disease with 18F-PI2620-PET
Objective: The aim of the study was to examine the potential of the second-generation tau-PET tracer 18F-PI2620 to detect tau deposition in anti-IgLON5 disease. Background:…
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