Genetic analysis of DNA methylation and hydroxymethylation genes in Parkinson’s disease
Objective: To investigate the relationship between DNA methylation/hydroxymethylation genes and Parkinson’s disease (PD), we conducted genetic analysis in a relatively large Chinese population. Background: PD…Examining supplementary motor area-primary motor cortex connectivity in tremor-dominant Parkinson’s disease using a novel transcranial magnetic stimulation protocol to inform clinical practice
Objective: Objectives: (1) Measure test re-test reliability of dual-coil transcranial magnetic stimulation (TMS) measures of supplementary motor area-primary motor cortex connectivity (SMA-M1 connectivity). (2) Investigate…How cognitive effort increases Parkinson’s tremor – an effictive connectivity fMRI study
Objective: To elucidate the neural mechanisms underlying tremor amplification during cognitive effort. Background: Parkinson’s tremor is related to cerebral activity in both basal ganglia and…Cerebral differences between dopamine-resistant and dopamine-responsive Parkinson’s tremor
Objective: To disentangle the cerebral mechanisms underlying dopamine-resistant versus dopamine-responsive tremor in Parkinson’s disease. Background: Parkinson’s rest tremor is related to cerebral activity in both…Asymmetrical striatal dopamine transporter binding correlates with excess contralateral rest tremor
Objective: To investigate the relationship between striatal dopamine transporter binding and rest tremor. Background: In vivo dopamine transporter imaging is a useful tool for distinguishing…Prevalence and Patterns of Rest and Action Tremor in Drug-naïve Parkinson’s Disease
Objective: We aimed to describe the prevalence and patterns of rest and action tremor in a large, prospective cohort of Parkinson’s disease (PD) patients. Background:…Evaluation of Childhood Tremor Electrophysiogically Influences Diagnosis and Treatment and Outcome
Objective: To report on the evaluation of childhood tremor in its many forms utilizing noninvasive electrophysiological recordings to differentiate clinical phenomenology from many entities thereby…Neurophysiologic characterization of Re-emergent tremor (RET) in Parkinson’s disease
Objective: To investigate: 1) the contribution of primary motor cortex (M1) to the generation of re-emergent tremor (RET) and rest tremor by measuring the Cortico-muscular…GluRδ2 protein reduction in cerebellar Purkinje cells contributes to the pathogenesis of essential tremor
Objective: To identify a molecular substrate reflecting kinetic tremor, the core feature of essential tremor (ET) Background: ET is one of the most common movement…Change of tremor dominant body side after deep brain stimulation in patients with Parkinson’s disease
Objective: In this study, we aimed to determine changes in distribution of tremor dominant body side after DBS and searched for possible explanations if tremor…