MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Wearing-off fluctuations"

  • 2025 International Congress

    30-year Delayed Diagnosis of Juvenile Parkinson’s Disease in a Patient Misdiagnosed with Dopa-responsive Dystonia

    N. Mohammed, J. Chen (New Brunswick, USA)

    Objective: To report a case of Juvenile Parkinson’s Disease (JP) misdiagnosed as dopa-responsive dystonia (DRD) and to emphasize the importance of early genetic testing in…
  • 2025 International Congress

    Clinical Features of Juvenile Parkinson Disease: a Comparative Study with Early-Onset Parkinson Disease

    L. Malfer, C. Piat, A. Mullan, K. Coffman, R. Savica (Rochester, USA)

    Objective: To describe a retrospective cohort of sixteen patients diagnosed with Juvenile Parkinson Disease and better define their family history, genetic profile, clinical progression, and…
  • 2025 International Congress

    Honey products in Parkinson’s disease – randomized placebo-controlled double-blind pilot study

    T. Endo, K. Toyooka, T. Matsumura, C. Mori, T. Saito, T. Saito, S. Sakoda (Toyonaka, Japan)

    Objective: The purpose of this study is to examine whether consumption of honey products can improve symptoms and their diurnal fluctuations in patients with Parkinson's…
  • 2025 International Congress

    Increase eye blink rate as a motor fluctuation in levodopa-Induced dyskinesia in parkinson’s disease a forgotten indicator of motor fluctuations a case report

    K. Salinas-Barboza, C. Alfaro-Tapia, JM. Altamirano (Mexico, Mexico)

    Objective: To recognize the increase eye blink rate (EBR) as a potential motor fluctuation (MF) in a PD patient undergoing levodopa treatment Background: A normal…
  • 2025 International Congress

    Efficacy and safety of Rotigotine Extended-Release Microspheres in Early Parkinson’s Disease

    H. Sun, X. Dan, H. Chen, J. Feng, W. Wang, Q. Ye, Y. Liu, C. Liu, S. Chen, P. Chan (Beijing, China)

    Objective: To assess the efficacy and safety of Rotigotine extended-release microspheres (LY03003) in patients with early Parkinson's disease Background: Treatment that provides a continuous flow of…
  • 2025 International Congress

    Evaluation of Local Field Potential-guided DBS-programming in a Parkinson’s disease outpatient clinic

    V. Zentsch, N. Warneke, I. Aymanns, D. Putzer, T. Huchtemann, T. Warnecke, I. Claus (Muenster, Germany)

    Objective: To evaluate potential use and applicability of local field potential-guided DBS-programming under real-life conditions in a Parkinson’s disease (PD) outpatient clinic. Background: Deep brain…
  • 2025 International Congress

    Computer Vision Quantification of Repeated Finger Tapping Demonstrates Aberrant Plasticity in Parkinson’s Disease

    D. Newbold, U. Kang (New York, USA)

    Objective: Test if symptoms of Parkinson's disease (PD) develop through aberrant plasticity. Background: Recent results in 6-hydroxydopamine-lesioned mice show that repeated performance of simple motor…
  • 2025 International Congress

    Opicapone for OFF Motor Fluctuations in Parkinson’s Disease: A Systematic Review and Meta-Analysis of Randomized Trials

    A. Fornari Caprara, J. Pitton Rissardo (Camden, USA)

    Objective: To evaluate the efficacy of opicapone 50 mg in reducing OFF time and improving motor function in Parkinson’s disease (PD) patients with motor fluctuations.…
  • 2025 International Congress

    Safinamide as an Adjunct Therapy for Motor Symptoms and ON-Time Extension in Parkinson’s Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

    A. Fornari Caprara, J. Pitton Rissardo (Camden, USA)

    Objective: To evaluate the efficacy of safinamide as an adjunct therapy in improving motor symptoms and extending ON-time in patients with Parkinson’s disease (PD). Background:…
  • 2025 International Congress

    Early Introduction of COMT Inhibitors at Low Levodopa Doses Improves Long-Term Motor Complications in Parkinson’s Disease: A sub-analysis of the REONPARK Study

    J. García-Caldentey, D. Vilas Roldán, L. López-Manzanares, H. Brigas, D. Martins, J. Reis, J. Blanco Ameijeiras, M. Rodríguez-de Miguel, I. Tegel Ayuela (Palma de Mallorca, Spain)

    Objective: This sub-analysis of the REONPARK study aims to identify predictive factors for the greater effectiveness of COMT inhibitors (COMTi) in alleviating motor complications in…
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