Objective: In this study, it is aimed to analysis of clinical features and  treatment efficiency  in patients with servical dystonia who are performed Botulinum injection and other therapies followed in Ege University Faculty of Medicine Hospital, Neurology Department Movement Disorder and Parkinson Clinic between 2006-2016 years.

Background:  In this study, we retrospectively reviewed patients with servical dystonia in terms of different aspects of disease and also effectiveness of teratment methods.

Methods: Hospital records of patients who botulinum toxin injection is performed for servical dystonia between 2006 -2016 are reviewed retrospectively. Patients are evaluated in terms of diagnosis, type of servical dystonia(simple, combined, complex, tonic and phasic), beginning time of the disease, if it is hereditary and there is also dystonia and type of dystonia, other treatments.

Results:   Idiopathic servical dystonia is seen in 118 patients, segmental dystonia in 6, generalized dystonia in 5, myoclonic dystonia in 4, tardive dystonia in 4, cerebral palsy in 2, Parkinson disease in 4 and multisystem atrophi in 1 patient. Family history is present in 15 patients but genetic analysis could not be performed.  Simple type cervical dystonia  is seen in 30 patients, combined type in 65, complex type in 29 patients. 106 of them shows tonic feature and 33 of them is  phasic. Blepharospasm is seen in 14 patients (11 women, 4 men), oromandibular dystonia in 5 (4 women, 1 man),  extremity dystonia in 5 (5 wmone, 8 men) and trunk dystonia in 5 (3 women, 2 men). Head tremor is detected in 44 patients (35 women, 9 men), postural and action tremor on extremity are seen in 16 patients (8 women, 8 men). Add on the botulinum  injection therapy, combination of clonazepam, biperiden and baclofen are given to 58 patients (41% of all patients, 40 of them (28%) are women, 18 are men (13%)), tetrabenazine is used in 4 patients (2.8% of all patients, 2 women(1.4%) and 2 men (1.4%)), deafferantation surgery is performed in 3 patients (2.4%) (2 women, 1 men) and pallidal stimulation in 12 patients (8.6% of all patients, 8 women (8.6%), 4 men (2.8%)). 

Conclusions: Our findings support that pallidal stimulation is beneficial therapy in servical dystonia cases.

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MDS Abstracts - https://www.mdsabstracts.org/abstract/clinical-analysis-of-patients-with-servical-dystonia-who-botulinum-toxin-injection-is-performed-10-years-experience-of-ege-university-neurology-department-of-movement-disorders-clinic/