Session Information
Date: Tuesday, September 24, 2019
Session Title: Parkinsonisms and Parkinson-Plus
Session Time: 1:45pm-3:15pm
Location: Agora 3 West, Level 3
Objective: This research aimed to study the bone mineral density (BMD) and vertebral pain in females with Parkinson’s disease (PD).
Background: PD and systemic osteoporosis are the most common age-related diseases leading to disability. Their combination is life threatening for older age patients.
Method: 104 women aged 50-74 years were included being divided into two groups: 1st group of patients without PD or any other illnesses/ conditions which may influence the bone (control group, n=54, average age 65.17±6.50 yrs.) and 2nd group of patients with PD (n=60, average age 66.40±8.21 yrs). The women from both groups did not differ significantly in main anthropometrical parameters and postmenopausal period duration. Bone mineral density was measured using dual-energy X-ray absorptiometry, T and Z-scores were calculated. Vertebral pain syndrome was assessed by visual analog scale (VAS).
Results: Our study showed an increased incidence of osteoporosis and significantly lower BMD at lumbar spine (0.97 ± 0.32 vs 1.09±0.13 g/cm^2, p < 0.0001), femoral neck (0.78 ± 0.13 vs 0.86±0.11 g/cm^2, p < 0.0001) and proximal femur (0.86 ± 0.16 vs 0.94±0.11 g/cm^2, p <0.05) in PD patients compared to the parameters of control group. The vertebral pain intensity was significantly higher in PD patients (4.75±2.76 cm) compared to females of control group (2.76±2.43 cm, t = 4.64; p < 0.0001). In addition, we found reliable correlation between VAS and T-score (r = - 0.32, p < 0.05) and Z-score (r = - 0.40, p < 0.05) of lumbar spine in PD females in contrast to control group patients who showed no relationship between pain and BMD.
Conclusion: Current study demonstrated significant differences between bone mineral density in the lumbar spine, femoral neck and proximal femur in women with PD, compared to control group, higher vertebral pain and relationship between pain intensity and bone mineral density in PD women.
To cite this abstract in AMA style:
I. Karaban, V. Povoroznyuk, M. Bystrytska, N. Karasevich, N. Grygorieva. Vertebral pain and bone mineral density in women with Parkinson’s disease [abstract]. Mov Disord. 2019; 34 (suppl 2). https://www.mdsabstracts.org/abstract/vertebral-pain-and-bone-mineral-density-in-women-with-parkinsons-disease/. Accessed May 29, 2025.« Back to 2019 International Congress
MDS Abstracts - https://www.mdsabstracts.org/abstract/vertebral-pain-and-bone-mineral-density-in-women-with-parkinsons-disease/