Category: Parkinson's Disease: Cognitive functions
Objective: This study aims to find associations between executive function, anxiety, depression, and reactive and anticipatory postural control domains.
Background: Cognition and emotional state are domains that highly interfere with postural control in Parkinson’s disease (PD) patients.
Method: In this cross-sectional study, thirty-four PD patients were thoroughly assessed for postural control in perturbed, quiet standing, and stepping initiation. To measure the postural response (PR), participants had to recover a stable balance of orthostatic posture in response to backward translation of the support base. The Ethics Committee of the School of Physical Educations and Sport of the University of São Paulo approved the study protocol. To measure anticipatory postural adjustments (APA), participants took a step initiation by moving their right foot after a beep. The following scales were performed: Montreal Cognitive Assessment (MoCA), Frontal Assessment Battery (FAB), Stroop test part III (Stroop-III), Digit Symbol Substitution Test (DSST), Trail Making Test B (TMTB), Hospital Anxiety and Depression Scale (HADS) has two subscales, the Hospital Anxiety Scale (HAS) and the Hospital Depression Scale (HDS). We performed multiple linear stepwise regression using postural variables as dependent and cognitive/emotional as independent variables.
Results: The results showed that cognitive flexibility explained 23% of anticipatory postural adjustments (APA) duration, inhibitory control explained 42% of instability on a malleable surface, and anxiety explained 21% of APA amplitude and 38% of reactive postural response amplitude.
Conclusion: Our results highlight the impact of emotional and cognitive states on particular domains of postural control in patients with PD. These results may have significant implications for targeting future treatments, mainly considering the predictors for postural control domains, which were consistent with the assumption that impairments in affective and executive domains underlie posture.
To cite this abstract in AMA style:
A. Bitiati, C. de Oliveira, C. de Souza, A. Batista, R. Marquesini, A. Moreira-Neto, C. Batista, L. Teixeira, A. Pardini, D. Coelho. Correlation between cognitive/emotional factors and postural control in patients with Parkinson’s disease [abstract]. Mov Disord. 2022; 37 (suppl 2). https://www.mdsabstracts.org/abstract/correlation-between-cognitive-emotional-factors-and-postural-control-in-patients-with-parkinsons-disease/. Accessed May 13, 2025.« Back to 2022 International Congress
MDS Abstracts - https://www.mdsabstracts.org/abstract/correlation-between-cognitive-emotional-factors-and-postural-control-in-patients-with-parkinsons-disease/