Session Information
Date: Wednesday, September 25, 2019
Session Title: Phenomenology and Clinical Assessment of Movement Disorders
Session Time: 1:15pm-2:45pm
Location: Les Muses Terrace, Level 3
Objective: Parkinson is mainly developed due to neurodegeneration of substantia nigra pars compacta (SNpc).the aim of our study was to check if there is any correlation between the size of SN and UPDRS.
Background: Since substantia nigra is the main affected part in Parkinson disease; if some similarity was found with UPDRS points; it may be used as a definite monitoring tool to assess disease progression in Parkinson patients. Accordingly in current study the substantia nigra measurement was compared with UPDRS in Parkinson patients.
Method: In this descriptive comparative cross-sectional study 60 consecutive idiopathic Parkinson patients attending to a general training hospital in 2015 were enrolled. The patients underwent trans-cranial Doppler ultrasonography via temporal bone window by single blind neurologist with Phased-Array Ultrasound System with 2.5 MHZ transducer and penetration depth of 14 to 16 centimeter to measure SN size which was compared with UPDRS.
Results: The results revealed that mean SN size was not significantly differed (P=0.377) according to dyskinesiaand freezing grading (P=0.781). SN size was not correlated to UPDRS (P=0.381; r=- 0.115).
Conclusion: Totally, according to this study, it may be concluded that there is no significant correlation between substantia nigra measurement and UPDRS.
To cite this abstract in AMA style:
N. Mohammadzade, F. Omrani, A. Habibi. Correlation between substantia nigra measurement and UPDRS [abstract]. Mov Disord. 2019; 34 (suppl 2). https://www.mdsabstracts.org/abstract/correlation-between-substantia-nigra-measurement-and-updrs/. Accessed May 18, 2025.« Back to 2019 International Congress
MDS Abstracts - https://www.mdsabstracts.org/abstract/correlation-between-substantia-nigra-measurement-and-updrs/