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Evaluating the Clinical Efficacy of the Personal KinetiGraph Movement Recording System

A. Fowler, K. Lyons, V. Sharma, R. Pahwa (Kansas City, KS, USA)

Meeting: 2017 International Congress

Abstract Number: 675

Keywords: Deep brain stimulation (DBS), Parkinsonism, Wearing-off fluctuations

Session Information

Date: Tuesday, June 6, 2017

Session Title: Technology

Session Time: 1:45pm-3:15pm

Location: Exhibit Hall C

Objective: To examine the clinical efficacy of the Personal KinetiGraph (PKG) movement recording in identifying patients with Parkinson’s disease (PD) requiring treatment for motor symptoms.

Background: The PKG is a wrist-worn monitoring device designed to assist clinicians in identifying patients with PD who may require treatment adjustments based on objective measurements of bradykinesia, dyskinesia, and motor fluctuations. PD patients with a Dyskinesia Score (DKS) greater than 9, and/or a Bradykinesia Score (BKS) greater than 26, and/or a Fluctuation and Dyskinesia Score (FDS) greater than 12.8 recorded by the PKG may have uncontrolled motor symptoms (Horne, McGregor, & Bergquist, 2015). The clinical symptomology of patients who meet the above criteria may warrant PD therapy adjustments.

Methods: Twenty-six patients with PD were evaluated by a movement disorder specialist for advanced therapy, including either deep brain stimulation or carbidopa/levodopa enteral suspension. Patients wore the PKG Data Logger for six full days. At the end of the six days, a summary report was generated and analyzed. 

Results: All of the patients (n = 26; 16 males, 10 females), ages 44 to 76 (M = 65.1 years, SD = 9.4 years), met clinical criteria for advanced therapy. Sixteen of the 26 patients met the above criteria by PKG for additional therapy (61.54%). Of the 10 patients who did not meet the above criteria, the BKS score ranged from 18.6 to 25.9, the DKS score ranged from 0.6 to 7.3, and the FDS score ranged from 7.3 to 11.5.

Conclusions: In our sample, over half of the patients met the above PKG criteria for treatment; however, these criteria should be further defined to more closely match clinical criteria for treatment.

References: Horne, M. K., McGregor, S., & Bergquist, F. (2015). An objective fluctuation score for Parkinson’s disease. PloS one, 10(4), e0124522.

To cite this abstract in AMA style:

A. Fowler, K. Lyons, V. Sharma, R. Pahwa. Evaluating the Clinical Efficacy of the Personal KinetiGraph Movement Recording System [abstract]. Mov Disord. 2017; 32 (suppl 2). https://www.mdsabstracts.org/abstract/evaluating-the-clinical-efficacy-of-the-personal-kinetigraph-movement-recording-system/. Accessed June 15, 2025.
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