Session Information
Date: Monday, October 8, 2018
Session Title: Parkinson's Disease: Non-Motor Symptoms
Session Time: 1:15pm-2:45pm
Location: Hall 3FG
Objective: Our aim is to evaluate the effects of Subthalamic Nucleus (STN)-DBS on the quality of life in PD patients by using the Gastrointestinal Quality of Life Index (GIQLI).
Background: Although PD leads to motor symptoms, a lot of patients suffer by a wide range of nonmotor symptoms. Deep Brain Stimulation (DBS) surgery is well established surgical therapy for treating the symptoms of patients with Parkinson’s disease (PD). Several reports claimed that the STN-DBS may led to improvement especially on nonmotor complaints like dyspepsia, constipation, and gastrointestinal motility. We preferred to use GIQLI test for evaluating the GIS complaints and the quality of life in patients that underwent STN-DBS and there are limited number of publications in the literature about this issue.
Methods: 26 patients who underwent STN-DBS because of PD were included in this study. The patients were evaluated before surgery and 3 months after surgery by GIQLI test. The medications history were compared too.
Results: When the preoperatif mean GIQLI score was 84.48±6.19, postoperative mean GIQLI score was found as122.89±3.34 (Table-1). The difference between the preoperative and postoperative results, was statistically significance. Also after the DBS surgery the number of patients who needs medications for the gastrointestinal system (GIS) complaints were found decreased significantly.
Conclusions: STN-DBS leads to improve the quality of life in PD patients especially by reducing the GIS complaints.
References: 1. Fasano A, Daniele A, Albanese A. Treatment of motor and non-motor features of Parkinson’s disease with deep brain stimulation. Lancet Neurol. 2012; 11(5): 429-42. 2. Prakash KM, Nadkarni NV, Lye WK, Yong MH, Tan EK. The impact of non-motor symptoms on the quality of life of Parkinson’s disease patients: a longitudinal study. Eur J Neurol. 2016; 23(5): 854-60.
To cite this abstract in AMA style:
A. Yilmaz, E. Okuyucu, M. Ugur. Evaluation of the Effect of STN-DBS on the Gastrointestinal Symptoms in Patients with Parkinson’s Disease via GIQLI [abstract]. Mov Disord. 2018; 33 (suppl 2). https://www.mdsabstracts.org/abstract/evaluation-of-the-effect-of-stn-dbs-on-the-gastrointestinal-symptoms-in-patients-with-parkinsons-disease-via-giqli/. Accessed June 14, 2025.« Back to 2018 International Congress
MDS Abstracts - https://www.mdsabstracts.org/abstract/evaluation-of-the-effect-of-stn-dbs-on-the-gastrointestinal-symptoms-in-patients-with-parkinsons-disease-via-giqli/