Skin could be the new peripheral tissue of interest in Parkinson’s disease transcriptomics
Objective: Profiling gene expression changes in peripheral tissues in PD. Background: Obtaining tissue for gene expression analysis in PD from CNS is done post mortem.…Synchronization Study of Regional Local Field Potential in Rat with Dopamine Receptor Stimulation
Objective: The aim of this study attempts to explore the non-linear interaction with cross-frequency coupling in rats during the stimulation of dopamine receptors. Background: Investigating…Dopamine substitution increases connectivity between premotor and motor areas in Parkinson’s disease – a DCM-Study
Objective: To assess the influence of dopaminergic depletion in Parkinson’s disease (PD) on connectivity parameters within the cortical motor network. Background: Integration of neuronal information…The interaction between iron metabolism and inflammation in Parkinson´s disease: an in vivo and post mortem study
Objective: To assess the relationship iron and inflammatory markers in an in vivo and post mortem study of Parkinson´s disease subjects. Background: Although neuroinflammation and…Pathological role of GBA2 in GBA1-related disorder
Objective: This study was performed to determine the pathological role of the non-lysosomal β-Glucosidase (GBA2) in the CNS in Gaucher’s disease (GD) and GBA1-related Parkinson's…Translation of a subject-specific stereotaxic platform to a large animal deep brain stimulation research models
Objective: To evaluate the feasibility and accuracy of applying the commercially-available, FHC STarFix platform system for direct targeting of deep brain stimulation electrodes in a…Mitigation Effects of a Novel Herbal Medicine Hepad, on neurophysiology.
Objective: Therefore, further studies are needed to identify compounds that can modulate the disease process and prevent the progression of symptoms in affected patients. Our…Blood Metagenomics Analyses of Brazilian Parkinson’s Disease Patients: A Clinical Substype Study
Objective: The goal of this study is to analyze the dormant microbiome present in blood of Parkinson’s disease (PD) patient and healthy controls samples by…Weighting fibroblasts for future diagnostic prospect
Objective: To determine the dry mass of fibroblasts obtained from apparently healthy individuals and patients with brain disorders or cancer pathologies for future diagnosis prospect.…Spiral Analysis Evaluates the Effects of Deep Brain Stimulation in Parkinson disease and Essential Tremor
Objective: To apply computerized spiral analysis to investigate upper limb kinematics and impact of deep brain stimulation (DBS) on motor dysfunction in Parkinson disease (PD) and…
