The effect of age on Substantia Nigra Hyperechogenicity in PD patients and healthy controls
Objective: To analyze whether the size of SN+ is differentially affected depending on disease start side. Secondly to analyze the interaction between a range of…Effects of subthalamic nucleus deep brain stimulation in Parkinson’s disease are mediated by a prefronto-cerebellar-striatal loop
Objective: To determine DBS-related changes of a motor network using resting state fMRI in PD patients with chronic STN-DBS. Background: In Parkinson’s disease (PD), dopamine…Resting-state connectivity and cognitive changes in Parkinson’s disease: A four-year follow-up study
Objective: To study functional connectivity changes using graph theory and their association with cognitive evolution in a sample of non-demented Parkinson’s disease (PD) and matched…Resting state fMRI points to disparate brain network activations in early Parkinson’s disease
Objective: To perform an exhaustive comparison of brain networks identified through functional MRI (fMRI) in a small cohort of patients with idiopathic Parkinson’s disease (IPD)…A longitudinal PET study to assess progression of laterality in Parkinson’s disease
Objective: This study aims to identify in Parkinson’s disease (PD) whether striatal dopamine transporter (DAT) losses occur at a similar rate in both sides of…Motor cortical inhibitory and facilitatory circuit interactions in Parkinson’s disease
Objective: To determine how intracortical circuits interact with one another in Parkinson’s disease. Background: Using transcranial magnetic stimulation (TMS), previous work has established that motor…Impaired topographic organization in cognitively unimpaired drug-naïve patients with rigidity-dominant Parkinson’s disease
Objective: To investigate the disrupted topographic organization in a cohort of cognitively unimpaired drug-naïve patients with rigidity-dominant Parkinson’s disease (PDAR), and its potential relationships with…Study on feasibility to develop a central nervous system (CNS) Leucine-rich repeat kinase 2 (LRRK2) PET tracer
Objective: To assess feasibility of developing a CNS LRRK2 PET tracer. Background: LRRK2 enzyme belongs to the leucine-rich repeat kinase family. Pathogenic mutations in the…Potential indicator of antiparkinsonian drug efficacy: an attempt to explore imaging findings
Objective: To clarify the Single photon emission computed tomography (SPECT) findings for evaluating currently unknown antiparkinsonian drug efficacy in Parkinson’s disease (PD) patients. Background: Little…Semi-automated segmentation and quantification of the substantia nigra depigmentation in Parkinson’s disease – a multicentre case control MRI study in 284 participants
Objective: To provide a semi-automated segmentation and quantification method of the changes in the substantia nigra (SN) in Parkinson’s disease (PD) using neuromelanin (NM)-sensitive MRI…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.