Salivary Alpha-Synuclein and tau in Parkinson’s Disease and Progressive Supranuclear Palsy
Objective: The aim of this study is to measure alpha-synuclein (a-syn) total, a-syn oligomers (a-syn olig) and total tau protein concentration in the saliva of…Alteration of the fecal microbiota in Chinese patients with Parkinson’s disease
Objective: Emerging evidences suggest that gut microbiota dysbiosis plays a role in Parkinson’s disease (PD). However, the alterations in fecal microbiome in Chinese PD patients…Validation of protein phosphatases that regulate the LRRK2 phosphorylation cycle
Objective: To identify and validate candidate phosphatases regulating the LRRK2 phosphorylation cycle. Background: Mutations in the gene encoding leucine-rich repeat kinase 2 (LRRK2) are one…New evidence for thalamic dysfunction in Parkinsonian rats
Objective: Abnormal oscillatory activity within the cortico-basal ganglia (BG)-thalamo-cortical circuit has been observed in Parkinsonian state, especially of β and γ bands (βB and γB).…Low body weight is associated with poor functional status in Parkinson’s disease (PD)
Objective: To assess if low body weight and malnutrition is associated with poor functional status in PD. Background: It has been observed that many advanced…Effects of neural stem cell transplantation on the differentiation of dopaminergic neurons in the substantia nigra and changes to rotational behavior of Parkinson’s disease rats
Objective: To explore the effects of neural stem cells transplantation on the differentiation of substantia nigra dopaminergic neurons and on the rotational behavior in a…Bidirectional gut-to-brain and brain-to-gut propagation of α-synuclein pathology in non-human primates
Objective: The prototypic synucleinopathy Parkinson's disease (PD) is hypothesized to spread out from the enteric nervous system (i.e. the gut) via the vagal nerve up…Relationship of Vitamin D deficiency with Parkinson’s disease risk
Objective: To study the level of vitamin D in the serum of Parkinson’s disease patients in the involvement of disease risk. Background: The Parkinson’s disease…Substantia nigra hyperechogenicity is similarly enlarged in Gaucher and in GBA mutation carriers
Objective: Testing the role of glycolipid accumulation in the risk for Parkinson's disease. Background: Increased risk for Parkinson's disease is well known among carriers of…Risk estimation in the years preceding diagnosis of Parkinson’s disease in the PREDICT-PD cohort
Objective: To test and refine the use of probability-based algorithms to identify individuals at high-risk of developing Parkinson’s disease (PD). Background: Neurodegeneration preceding a formal…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.