Effects of Glial Heme Oxygenase-1 on Neuronal Alpha-Synuclein in the GFAP.HMOX1 Mouse Model of Parkinson’s Disease
Objective: To determine whether astroglial HO-1 transduces environmental and endogenous stressors into patterns of neural damage which promote the toxicity of neuronal alpha-synuclein. Background: The…Motor Symptoms in Patients with Parkinson’s Disease – Correlations with Cerebrospinal Fluid C-Reactive Protein
Objective: In this study, we intended to investigate the association between severity of PD motor symptoms and the cerebrospinal fluid (CSF) levels of CRP using…A patient with myotonic dystrophy type 1 and parkinsonism
Objective: We report the first case of myotonic dystrophy (DM) type 1 with DMPK mutations presenting with parkinsonian syndrome. Background: DM type 1 is a…Enhancing protein palmitoylation is protective in alpha-synuclein dependent cytotoxicity
Objective: To determine if enhancement of protein palmitoylation benefits alpha-synuclein (aS) dependent vesicular trafficking defects and cytotoxicity. Background: Recent studies suggest that vesicular trafficking defects…STN DBS – A study of frequency of gait (fog) in Parkinson’s disease
Objective: In search of new techniques to help improve lifestyle of Parkinson`s diseased conditions (PDs), a wireless technique is proposed to identify freeze, reduce freeze,…A post-mortem and in vivo study of neuroinflammation and Toll like-receptors in Parkinson’s disease
Objective: To investigate inflammatory change and Toll-like receptor (TLR) expression in human post-mortem Parkinson’s disease (PD) brains and to test the efficacy of TLR-blocking agents…Antibodies to alpha-Synuclein in Parkinson disease
Objective: Alpha-synuclein (α-syn) plays a very important role in pathogenesis of Parkinson’s disease (PD). There are enough evidence of neuroinflammation in the brain tissue of…Carrier Mediated Delivery System Bearing Dopamine for Effective Management of Parkinsonism
Objective: In the present investigation, amino acid coupled liposome bearing dopamine-HCl were prepared to deliver drug to the brain utilizing receptor-mediated transcytosis for effective management…Speech intelligibility and comprehensibility in Slovak patients with Parkinson’s disease
Objective: The aim of our study was to evaluate intelligibility and comprehensibility (intelligibility in context) and its relationship with MDS-UPDRS (sub)scores in Slovak population of…Partial depletion of peripheral M1 macrophages ameliorates the neuroinflammation and dopaminergic neuronal death in the brain of a MPTP-induced mouse model of PD
Objective: Neuroinflammation in the PD brain involves the activation of microglia and the increasing levels of inflammatory cytokines. Several studies have shown that the peripheral…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.