Measuring disease progression with neuroimaging in MSA-a systematic review
Objective: To assess longitudinal changes of serial neuroimaging-derived parameters in MSA. Background: Different neuroimaging modalities hold potential as surrogate markers of neurodegeneration in multiple system…Imaging Brain Insulin Resistance in Parkinson’s Disease using [¹⁸F]FDG-PET
Objective: To obtain a glucose brain uptake survey of Parkinson's Disease (PD) patients with or without insulin resistance (IR). Background: IR is common in PD…Cortical and subcortical atrophy in typical and variant Parkinson-plus syndromes: PROSPECT-M-UK study
Objective: To investigate grey matter volume in typical and variant Parkinson-plus syndromes, to correlate these with disease severity, and to assess regional atrophy within disease…No link between striatal dopaminergic axons and dopamine transporter imaging in Parkinson’s disease
Objective: The objective of this study was to investigate if dopamine transporter (DAT) binding is associated with dopaminergic neurites in the putamen. Background: Dopamine transporter…Association of MRI-derived estimated brain age and cognitive ability in Parkinson’s disease
Objective: To characterise MRI-derived structural age-related brain health in Parkinson’s disease (PD) patients as a function of cognitive ability. Background: Normal ageing produces a stereotypical…“Brain-first” vs. “body-first” Parkinson’s disease is determined by RBD-status – a multi-modality imaging study
Objective: In a multi-modality imaging study, we test the hypothesis that Parkinson’s disease (PD) can be divided into two strikingly distinct phenotypes: (1) PD patients,…Association between sleep disturbances in Parkinson’s disease and bioimaging
Objective: We investigated whether bioimaging for Parkinson’s disease (PD) such as metaiodobenzylguanidine (MIBG) myocardial scintigraphy and 123I-ioflupane SPECT (DaTSPECT) are useful for biomarker of sleep…Primary disruption of the subsystems of the default mode network in drug-naïve Parkinson’s disease with mild cognitive impairments: a resting-state functional connectivity MRI study
Objective: To study changes in subsystems in drug-naïve Parkinson’s disease with mild cognitive impairments using resting-state functional connectivity MRI. Background: Mild cognitive impairment (MCI) is common…Fractional anisotropy patterns in non-demented Parkinson’s disease patients using hierarchical cluster analysis
Objective: We aim to characterize PD subtypes using a hypothesis-free, data driven approach based on fractional anisotropy (FA) measures. Background: Clinical variability in the Parkinson’s…Opposing effects of levodopa on basal ganglia activity in Parkinson’s disease during motion and rest
Objective: To explore the pattern of activation within the motor network during the movement and resting phases of the tapping task in Parkinson’s disease (PD)…
